Abstract: AIM:To observe the restoration action of topical Fum extract (FumE) on skin destruction. METHODS:The skin destruction on rats was caused by ultraviolet radiation. The changes of body weight and skin appearance of rats were compared, and the content of MDA and the activity of SOD were measured. The burn on rats was caused by sodium hydroxide, the growth rate of weight and the healing time were recorded. RESULTS:FumE could relieve the skin destruction caused by ultraviolet radiation, reduce the content of MDA and increase the activity of SOD. FumE could shorten the healing time of rats burned by sodium hydroxide. CONCLUSION:FumE has protective effects on skin destruction caused by ultraviolet radiation, and can repair raw surface caused by sodium hydroxide.

Key words: Fum extract, skin destruction, reparation