Systematic review on randomized controlled trials for treatment of ventricular premature beat(VPB) by ShensongYangxin capsule

Abstract

Abstract: AIM: To evaluate the curative effect difference between ShensongYangxincapsule and Con-trol Group and the safety of them on ventricular prema-ture beat (VPB) .METHODS: Meta-analysis of 21-ShensongYangxin Capsule on the parameters commonly used treatment of VPB and other research literature on drug treatment of VPB, its effectiveness and safety for homogeneity test and the combined effect size estimate. RESULTS: Homogeneity test :Clinical effectiveness of the ECG :χ²=25.20, df=17, P=0 .090;Clinical ef-fectiveness:χ²=26.10, df=11, P=0.006;Clinical effectiveness of ventricular premature beats:χ²=7.13, df=5, P=0.211;Security 1 χ²=31.14, df=20, P=0.053, Security 2χ²=30.37, df=20, P=0.064.Combined effect size estimates: Effectiveness: Clinical effectiveness of the ECG:OR affiliate=1.04, 95%confidence interval of OR was [1.00, 1.09], Clinical effectiveness: OR affiliate=1.33, 95% confi-dence interval of OR was [1.19, 1.48] , Clinical ef-fectiveness of ventricular premature beats:OR affiliate=1.25, 95 % confidence interval of OR was [1 .13, 1.39] , Security 1 :OR affiliate=0.38, 95% confi-dence interval of OR was [0.28, 0.52] , Security 2: OR affiliate=0.39, 95% confidence interval of OR was [0.29, 0.52].CONCLUSION: The treatment of VPB ShensongYangxin capsule is better than the control group, Comparison of safety is also better control group and there is a significant difference .

Key words: ShensongYangxin capsule, ventricular premature beat, Meta analysis, randomized controlled trial, systematic review

CLC Number:

R311

LI Yan-hong, ZHU Huai-jun. Systematic review on randomized controlled trials for treatment of ventricular premature beat(VPB) by ShensongYangxin capsule[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2009, 14(8): 915-923.

References

[1] 王彦方, 郑晓辉, 都增光.参松养心胶囊治疗室性期前收缩疗效临床观察[J] .疑难病杂志, 2006, 5(2):124-125.
[2] 郑立文, 段英春, 陈立忠.参松养心胶囊治疗功能性室性早搏疗效观察[J] .长春中医药大学学报, 2007,23(4):38-39.
[3] 黄显南, 黄照河, 陆克兴, 等.参松养心胶囊治疗冠心病室性期前收缩临床观察[J] .吉林医药学院学报, 2007, 28(2):91-92.
[4] 李桂娥, 卢满祥.参松养心胶囊治疗冠心病室性早搏疗效观察[J] .现代中西医结合杂志, 2008, 17,(34):5307-5308.
[5] 徐贵成, 霍保民, 吴以岭, 等.参松养心胶囊治疗冠心病室性早搏随机双盲、阳性药对照、多中心临床研究[J] .中国中医基础医学杂志, 2003, 9(3):37-40.
[6] 杜荣品, 吕妍琨, 王立立.参松养心胶囊治疗急性冠脉综合征室性早搏的临床观察[J] .疑难病杂志,2007, 6(6):354-355.
[7] 邹文淑. 参松养心胶囊治疗老年冠心病室性早搏120 例临床观察[J] .疑难病杂志, 2009, 8(3):149-151.
[8] 王新广. 参松养心胶囊治疗慢性心力衰竭室性早搏临床观察[J] .中国实用医药, 2007, 2(32):331.
[9] 侯彩娜, 张翠平, 张敬.参松养心胶囊治疗室性期前收缩 86 例疗效观察[J] .现代医药卫生, 2009, 25(1):106-107.
[10] 杨剑, 应淑琴.参松养心胶囊治疗室性期前收缩疗效观察[J] .现代中西医结合杂志, 2008, 17(31):4837-4838.
[11] 彭卫国. 参松养心胶囊治疗室性早博 68 例疗效观察[J] .中医药导报, 2008, 14(11):42-43.
[12] 黄昌凯, 肖俊英, 秦淑娟 .参松养心胶囊治疗室性早搏 142 例临床观察[J] .中国社区医师, 2008, 24:35.
[13] 赵文艺. 参松养心胶囊治疗室性早搏 162 例疗效观察[J] .中国医疗前沿, 2009, 4(2):88.
[14] 邹建刚, 曹克将, 李东野, 等.参松养心胶囊治疗室性早搏的多中心随机对照研究[J] .疑难病杂志,2007, 6(3):138-140.
[15] 梁留峰, 李惠霞, 杨杰.参松养心胶囊治疗室性早搏的疗效观察[J] .中国医药导报, 2009, 6(6):29-30.
[16] 王彦新, 王超, 郑晓群, 等.参松养心胶囊治疗室性早搏的临床观察[J] .黑龙江医学, 2008, 32(7):525-526.
[17] 张爱君, 邱清华.参松养心胶囊治疗室性早搏的临床疗效观察[J] .中国现代医生, 2008, 46(2):72-73.
[18] 秦方, 闫亚非, 吴时达 .参松养心胶囊治疗室性早搏疗效观察[J] .实用医院临床杂志, 2007, 4(4):90-91.
[19] 刘会珍. 参松养心胶囊治疗室性早搏临床分析[J] .中外医疗, 2008, 16:73.
[20] 周素苓. 参松养心胶囊治疗室性早搏临床观察[J] .现代中西医结合杂志, 2007, 16(20):8382.
[21] 付永勇, 黎考盛.稳心颗粒与参松养心胶囊治疗室性早搏疗效比较[J] .社区医学杂志, 2008, 6(11):76-77.
[22] 靳颖华, 张卫东, 齐平.痰热清注射液治疗支气管炎的 Meta 分析[J] .首都医药, 2008, 12:30-31.
[23] 杨佳丹, 欧阳净.文拉法辛与氟西汀治疗抑郁症疗效比较的 Meta 分析[J] .中国神经精神疾病杂志,2009, 35(1):30-34.
[24] Lafuente-Lafuente C, Mouly S, Longás-Tejero MA, et al.Antiarrhythmic drugs for maintaining sinus rhythm after cardioversion of atrial fibrillation:a systematic review of randomized controlled trials[J] .Arch Intern Med, 2006,166(7):719-728.
[25] 侯应龙. 抗心律失常药物的致心律失常作用[J] .中国心脏起搏与心电生理杂志, 2007, 21(1):14-16.
[26] 郭来. 室性早搏中医药治疗进展[J] .中国中医急症, 2008, 17(10):1445-1446.
[27] 李宁, 吴相锋, 马克娟, 等.参松养心胶囊对心室肌细胞钾通道的影响[J] .疑难病杂志, 2007, 6(3):133-137.
[28] 陆春玲, 李建军, 黄涛, 等.参松养心胶囊治疗 Duch-enne 型肌营养不良症早期心肌损害疗效观察[J] .中成药, 2007, 29(11):1579-1581.
[29] 王蕾, 陈琼, 范超平 .参松养心胶囊治疗脑卒中后失眠症的疗效观察[J] .中国实用神经疾病杂志,2007, 10(5):108.
[30] 吴相锋, 张树林.参松养心胶囊治疗围绝经期综合征临床观察[J] .中国中医药信息杂志, 2007, 14(10):52.
[31] 孙传岐, 刘跃文.参松养心胶囊治疗高脂血症 65 例临床观察[J] .白求恩军医学院学报, 2006, (4):214-215.
[32] 狄长华, 武维恒, 高尊敬.胺碘酮与慢心律对冠心病室性心律失常的疗效分析[J] .井冈山医专学报,2004, 11(1):48-49.