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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2011, Vol. 16 ›› Issue (6): 695-698.

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Effect of Nrf2-ARE pathway in the heart ischemic injury

XU Yuan-qing, HE Hai-bo, ZHANG Chang-cheng, WANG Hong-wu, YUAN Ding   

  1. Medical Science College, China Three Gorges University, Yichang 443002, Hubei, China
  • Received:2011-03-12 Revised:2011-04-13 Published:2011-07-25

Abstract: Nrf2-ARE pathway is particularly important as an anti-oxidative stress pathway in recent years, the mechanism of signal pathway is intricate and general. More research suggests that it plays an important role in the pathogenesis of heart ischemic injury, and it will be an important potential target for treatment of heart ischemic injury. In summary, the physiological and pathophysiological function of Nrf2-ARE pathway and relation with heart ischemic injury has been reviewed.

Key words: Nrf2-ARE pathway, Heart ischemic injury

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