Abstract: AIM: To study the awareness of adverse drug reactions and Safe Drug Use knowledge in doctors, nurses, and pharmacists these three kinds of medical staff, thus providing reference for the development of adverse drug reaction and the clinical Safe Drug Use monitoring in depth.METHODS: We made a survey of questionnaire on the ADR and the Safe Drug Use knowledge, in medical personnel (doctors, nurses, pharmacists) from 45 clinical departments of a large 3A-Grade hospital in Anhui south region, by online survey conducted with online pharmacy survey platform. Data from the platform were derived form excel automatically, statistical analysis was performed using SPSS 19.0 software.RESULTS: The survey platform obtained 575 valid questionnaires. The average rate of awareness of medical staff on ADR and Safe Drug Use was 83.0%, and 83.4% on processes of reporting ADR. There were good awareness rate in medical personnel (doctors, nurses, pharmacists) on the basic concept of adverse drug reactions, medication errors, no significant difference was observed (P>0.05). However, the awareness rate on judgment of ADR / ADE, medication error was different significantly (P<0.001). The level of awareness of doctors, nurse was lower than that of pharmacists. On “countermeasures for treatment emergent ADR”, “mandatory items in reporting ADR”, there were no significant difference in types of medical personnel (P>0.05), however, they were different on answers to the stated time limit for ADR report (P<0.001), The awareness pharmacists was higher than the doctors and nurses.CONCLUSION: Comprehensive analysis demonstrate the level of three types of hospital staff is good overall, on the basic knowledge on the ADR and Safe Drug Use, but there are some concepts confusion on adverse drug reactions, adverse events, medication errors as well. Medical staff should improve knowledge of ADR and Safe Drug Use by various forms of training, education. as well as the judgment of the medical staff on ADR/ADE, medication errors, the level of ADR monitoring and reporting, so as to improve the level of rationality of medicine and safety.

Key words: Adverse drug reaction, Safe Drug Use, Survey