Abstract: AIM: To observe the effect of Shukang soup on Chronic pelvic inflammatory disease and investigate its possible mechanism.METHODS: The rat model was made by three kinds of bacteria mixed infection and mechanical damage. The rats were randomly divided into five groups: normal control group, model group, low dose group Shukang soup (1 mL/kg), high-dose group Shukang soup (1 mL/100g), Qianjinpian group (1.5 g/kg). After the last administration, Swelling of the uterus were observed and SOD, MDA and IL-1β, IL-6 and TNF-α were tested.RESULTS: Shukang soup can obviously reduce the degree of swelling of the uterus modeling rats, and MDA, IL-1β, IL-6 and TNF-α were reduced, SOD was increased.CONCLUSION: Shukang soup have a therapeutic effect on chronic pelvic inflammatory disease, this effect may be due to the inhibition of Oxygen free radical damage and inflammatory cytokines.

Key words: Shukang soup, chronic pelvic inflammatory disease, experimental study