Research progress of alopecia experimental model and its pharmacotherapeutics

Abstract

Abstract:

Alopecia is a kind of disease characterized by loss of hair. Pathophysiological mechanism of alopecia and its hair regeneration therapy is the pressing issues of current study. The successful replication of Alopecia experimental model plays a key role in promoting the study of pathological mechanism and pharmacotherapeutics. This review systematically describes the progress in alopecia animal model and in vitro organ model, which have been established at home and abroad. Based upon the aforementioned experimental models, some relevant applications in experimental therapeutics are simultaneously enumerated. Hopefully all these information facilitate the researchers according to the need to select the appropriate model to carry out the experiment.

Key words: alopecia, experimental model, spontaneous alopecia, drug-induced alopecia, full thickness skin graft induced alopecia, pharmacotherapeutics

CLC Number:

R965.1

JIN Jianbo, ZHANG Jianhua . Research progress of alopecia experimental model and its pharmacotherapeutics[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2017, 22(1): 115-120.

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