Interventive effect of preventing application of antibacterials during perioperative period in orthopedics

Abstract

Abstract:

AIM: To evaluate the rational use of antibacterials during the perioperative period of clean surgery before and after the implementation of standardized management in the department of orthopedics of a 3A hospital. METHODS: A retrospective study of orthopedic surgery was conducted from January to March in 2016 and from October to December in 2016. A comparative study was made on the prophylactic use of antibacterials during the perioperative period of clean surgery, antimicrobial use frequency, the rate of rational drug use, rational choice of indications, the first dose time of medication, the species selection of antibacterials and the course of medication. RESULTS: Through the standardized management, the rate of prophylactic use of antibacterials during the perioperative period of clean surgery was decreased, the selection of antibacterials tended to be reasonable, and the rate of rational use of antibacterials was significantly improved. The rate of rational choice of indications was reached more than 83%. The correct rate of first dose time was greatly improved as well as the species selection and the course of medication (P<0.01). CONCLUSION: The rationality of the use of antimicrobial agents in orthopedics is significantly improved after the intervention and the intervention achieves good results.

CLC Number:

R194

LI Jing, GAO Yunyun. Interventive effect of preventing application of antibacterials during perioperative period in orthopedics[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2017, 22(11): 1283-1291.

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