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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2019, Vol. 24 ›› Issue (2): 228-234.doi: 10.12092/j.issn.1009-2501.2019.02.018

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Advances in the treatment of tacrolimus in idiopathic membranous nephropathy

FANG Xi1, QU Qiang2, XIAO Xiangcheng1   

  1. 1 Department of Nephrology, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China;2 Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, China
  • Received:2018-10-08 Revised:2019-01-08 Online:2019-02-26 Published:2019-03-04

Abstract:

Tacrolimus is a calcineurin inhibitor that acts as an immunosuppressive agent. Idiopathic membranous nephropathy is the most common type of primary nephrotic syndrome. Compared with other immunosuppressive agents, tacrolimus has a smaller adverse effect and is more widely used in idiopathic membranous nephropathy. The application of tacrolimus in idiopathic membranous nephropathy has been studied in recent years. This paper summarizes the research progress of tacrolimus in idiopathic membranous nephropathy and its individualized usage.

Key words: tacrolimus, membranous nephropathy, immunosuppression, individualized medication

CLC Number: