Research progress of long noncoding RNA in systemic lupus erythematosus

doi:10.12092/j.issn.1009-2501.2018.04.018

Abstract

Abstract:

Long noncoding RNAs (lncRNA), play significant role in regulation of epigenetics, chromatin remodeling, transcription and post transcriptional regulation and immune system regulation. Nonetheless, it once was seemed as "noise gene" among the complex modification of genetic functions. lncRNA is involved in the regulation of differentiation, activation and secretion of cytokines. In this study, we mainly focus on the role of lncRNA in the regulation of systemic lupus erythematosus.

Key words: long noncoding RNA, systemic lupus erythematosus

CLC Number:

R593.24

CHEN Xinxin, CHEN Chaosheng. Research progress of long noncoding RNA in systemic lupus erythematosus[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2018, 23(4): 471-476.

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