Advance in research for pharmacokinetics and drug interactions of licorice

Abstract

Abstract: Licorice is one of the oldest and most frequently employed botanicals in Chinese medicine with multiple pharmacological effects, and a wide range of clinical application. But licorice can also cause adverse effects and drug interactions. A clear understanding of the chemical composition, disposition and drug interactions of licorice is contributed to promote its usage rationally and safely in clinic. In this paper, pharmacokinetics and drug interactions of licorice are reviewed and discussed in recent several decades, in order to get a more comprehensive understanding about licorice and ensure the safety of clinical medication.

Key words: Licorice, Chemical component, Pharmacokinetics, Drug interaction

CLC Number:

R969

CHEN Jiang-fei, XU Ping, ZHU Su-yan, HU Yi-jian. Advance in research for pharmacokinetics and drug interactions of licorice[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2010, 15(10): 1174-1182.

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