Abstract: AIM: To observe the effect of parenteral nutrition (PN) in the feeding of premature infants. METHODS: Seventy five premature infants were randomly assigned into three groups.The control group supplied glucose combined with minimal enteral nutrition and assisted with nonutrition sucking.In treatment groups:the no-fat emulsion PN group supplied amino acids and glucose combined with minimal enteral nutrition and assisted with nonutrition sucking, and the fat emulsion PN group supplied fat emulsion, amino acids and glucose combined with minimal enteral nutrition and assisted with nonutrition sucking.After 1 week, the weight, the state correlated biochemical indicator and complications were detected.RESULTS: Both of the no-fat emulsion PN therapy and the fat emulsion PN therapy could promote weight gain and lessen complications, and the clinical application was comparatively safe.CONCLUSION: The PN can improve growth and development of premature infants and elevate the clinical therapeutic efficacy.

Key words: premature infants, parenteral nutrition, minimal enteral nutrition