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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2007, Vol. 12 ›› Issue (6): 601-608.

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Relationship between β-adrenergic receptor genetic polymorphism and disease susceptibility as well as differences in drug response

LIU Jie, LIU Zhao-qian, ZHOU Hong-hao   

  1. Institute of Clinical Pharmacology, Central South University Xiangya School of Medicine, Changsha 410078, Hunan, China
  • Received:2007-06-02 Revised:2007-06-20 Published:2020-11-09

Abstract: β-adrenergic receptor is one subfamily belongs to G-protein coupled receptor, which modulates various physiologic functions in response to endogenous catecholamines and acts as a target for many drugs. This article elucidates mainly the relationship between β-adrenergic receptor genetic polymorphism and disease susceptibility as well as differences in drug response.

Key words: β-adrenergic receptor, genetic polymorphism, drug response

CLC Number: