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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2004, Vol. 9 ›› Issue (1): 8-12.

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Progress in research of brain natriuretic peptide and heart failure

CHEN Xie-Xing, HONG Hua-Shan, WANG Yi-Bo   

  1. Department of Cardiology, Union Hospital of Fujian Medical University, Institute of Coronary Heart Disease, Fuzhou 350001, Fujian, China
  • Received:2003-09-01 Revised:2003-10-12 Online:2004-01-26 Published:2020-11-16

Abstract: Brain natriuretic peptide (BNP) is synthesized and secreted chiefly from heart. It is a cardiac neurohormone specifically secreted from the ventricles in response to volume expansion and pressure overload. BNP is also a plasma marker for diagnosis, therapy and prognosis in patients with heart failure.

Key words: heart failure, brain natriuretic peptide, diagnosis, prognosis

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