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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 1998, Vol. 3 ›› Issue (2): 94-97.

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Effect of Gui Qi San andits separated prescription on immunoregulative effect in mice

ZHU Xiao-Xin, WANG Meng, WU Dun-Xu1, ZHANG Yu-Zheng1, GONG Bin1, FANG Zhao-Qin1, XU Pin-Chu1, WANG Ren1, XI Pei-Li1, LIAO Han1   

  1. Xiyuan Hospital, China Academy of Traditional Chinese Medicine, Beijing 100091;
    1Shanghai University of Traditional Chinese Medicine, Shanghai 200032
  • Received:1998-01-20 Revised:1998-02-20 Online:1998-06-26 Published:2020-12-01

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Abstract: Aim Theimmunoregula tive Effect of Gui Qi San andits separated prescription on immune functions of mice was to be studied.Methods Theeffect of Gui Qi San and its separated prescription only mphocytes was observed after theimmune function of mice was damaged by cyclophosphamide.Results They could evidently counteract mice spleen degeneration caused by cyclophosphamide or improve their life quality, promote immunosuppressied mice T.Blymphocytes proliferation, act ivate NK cells, increase CD4+/CD8+cells ratroby increasing CD4+ cell, and lowerecAMP level in spleen cell.Thecompo site prescription had bettereffectthan its separated prescription and PSP.It had no Effect on immune function of normal mice.Conclusion Gui Qi S an andits separated prescription hadimmunoregulative Effect on immunosuppressied mice.

Key words: Gui Qi San, separated prescription, lymphocytes, immunoregulation

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