Abstract: Aim To analy ze theprima ry drugs of compound 961, which is composed of 10 t raditional Chinese drugs.Methods Theexperimental design was made by theortho gonal t value method put forw ard by Sun WM and Sun RY.Results and Conclusion A simplif ied and more Effectiverecipe compound 962, consisting of 6 drugs was formulated and preparedandits pharmacological eff icacywas verfied.Theuse oforthogonal t value method merits wider application in studying mult iing redientrecipes of t raditional Chinese medicine.Thecharacteristics of thedisease, thepharmacolog ical Effects of thet raditional Chinese drugs, theuse of mult iple animal models and mutiple parameters are factors thatrequireconsideration in research.

Key words: orthogonal t value method, animal model