Abstract: Aim The clinical effect of mezlocillin, a new antibiotic int reatment of gonorrheae was observed and cempared with that of cefuro xime.Method The tested cases of gonorrheae were randomly divided into two groups treated by mezlocillin or cefuroxime.Results It was showed that the curetate in mezlocillin group (75%)was higher than that in cefuroxime group (70%)and the effective rates in both groups were 100%.The adverse reaction of mezlocillin was low and slight.Conclusion The mezlocillin is an effective and safe antibiotic int reatment of gonorrheae.

Key words: mezlocillin, gonorrheae, clinical trial