Abstract: A clinical trial of progestin-only contraceptive injectable Depo Geston in Chinese lactating and non-lactating women Hao Zhuanye Chen Sufang Yang Dan Zhou Huien Luo Shiyuan Lei Zhenwu Shao Qingxiang Sang Guowei (Damily Planning Research Institute, Zhejiang Academy of Medical Sciences, Hangzhou, 310013) Aim To evaluate the efficacy, side effects and acceptability of 3 monthly injectable contraceptive Depo Geston in lactating and non-lactating Chinese women. Methods All subjects were recruited in 3 clinics after giving datailed consultation and obtaining informed consent to receive im injection of Depo Geston at the 3 months interval for one year. Results No pregnancy occurred during one year study period. Overall discontin-uation rates for lactation and non-lactation women were 5. 05% and 11. 4%, respective-ly. The side effects mainly was irregular bleeding. The proportion of women complained of bleeding problems in non-lactation women(16. 1%) was higher than that in lactation women (5. 1%, P< 0. W). No other serious side-effects were observed. Conclusion Depo Geston is a highly effective, long-acting contraceptive, could have good acceptability after giving datailed advice. It is especially applicable to lactation women.

Key words: Depo Geston, DMPA, contraceptive, lactation