Study on the relationship between thyroid hormones and hepatic insulin resistance

Abstract

Abstract: Insulin resistance means the peripheral target tissue and cells of insulin have a decreased effect on endogenous or exogenous insulin sensitivity and reactivity, leading to physiological dose of insulin producing physiological effects below normal and appearing clinical manifestations of hyperinsulinemia, high blood sugar, high blood pressure, high cholesterol and other metabolic disorders. The normal thyroid function status is an important factor to maintain the normal glucolipid metabolism and insulin sensitivity and thyroid hormone levels are important in the formation of hepatic insulin resistance. This article summarizes the present study of the relationship between thyroid hormones and hepatic insulin resistance, aiming to provide a systematic and fundamental document for the follow-up research.

Key words: Thyroid hormone, Insulin resistance, Liver, Glucolipid metabolism

CLC Number:

JIANG Li, HE Bi-xia, DING Qi-long. Study on the relationship between thyroid hormones and hepatic insulin resistance[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2013, 18(3): 356-360.

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