Abstract: AIM: To investigate the ratio of prophylactic antibiotics in three kinds of type I incision operation.METHODS: Each 120 cases including thyroid surgery, breast surgery, inguinal herniorrhaphy from September to December in 2011 were analyzed.RESULTS: In the 360 cases, the ratio of antibiotics was 75.8%, the ratio of indication of prophylactic was 31.9%, the indication of prophylactic use timing is reasonable accounted for 71.4%.The main volume of solvent was 250 mL.CONCLUSION: There are main problems that the indication of prophylactic is low, the volume of solvent is too large in prophylactic antibiotics use in three kinds of type I incision operation. Some necessary intervention should be taken in order to promote the rational use of antibiotics.

Key words: Type I incision operation, Antibiotics, Investigation