Comparative study on nerve sparing radical hysterectomy with radical hysterectomy

Abstract

Abstract: AIM: To compare the life quality of patients after nerve sparing radical hysterectomy or traditional radical hysterectomy and evaluate the safety of two operations.METHODS: Fifty patients with cervical cancer ofⅠB-ⅡA(FIGO) were selected under the guideline of ethic committee.Thirty of them received traditional radical hysterectomy(RH)as control group and twenty received nerve sparing radical hysterectomy (NSRH)as experimental group.The excision extent, operation time, blood loss, urethral catheter remaining days, residual urine volume, the first exhaust time, defecation time and sexual function recovery were followed up for half a year and these data were compared between the two groups.RESULTS: On the tenth day after operation, the residual urine volume of control group and experimental group were (201.83±83.00) mL and (139.75±69.01)mL; the urethral catheter remaining days of control group was (15.20±2.43) d and the experimental group was (11.85±2.08) d; the first exhaust time was (72.97±16.31) h and(59.60±13.37)h;the first defecation time was (121.17±23.07) h and (91.05±11.66) h,there were statistically difference in two groups(P<0.05). The sexual dysfunction in control group and experimental group control group were 86.7%and 45%,respectively. For six months after operation there were statistically difference between two groups(P<0.05). 77.8% of patients who didn't resume intercourse were afraid of relapse and 55.6% of them were afraid of pain.The median operation time of the two groups were 250 (180-330) min and 205 (150-270) min,and there was no statistically difference between two groups in operation time, blood loss and excision extent.CONCLUSION: NSRH for the patients with cervical cancer is feasible and safe and it can improve the recovery of bladder and rectum functions, and eventually make contribution to quality life of patients.

Key words: Nerve pelvic sparing, Radical hysterectomy, Quality life, Sexual function

CLC Number:

R713

TANG Xiu-wu, SUN Yun, NI Guan-tai. Comparative study on nerve sparing radical hysterectomy with radical hysterectomy[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2013, 18(10): 1148-1154.

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