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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2014, Vol. 19 ›› Issue (10): 1144-1148.

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Impact of interaction between smoking and tea drinking on susceptibility to tuberculosis

CHEN Meng-shi1, SU Cong-xu2, WANG Mian1, LIANG Ying1, TAN Hong-zhuan1   

  1. 1 Department of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha 410008,Hunan,China;
    2 Yueyanglou Center for Disease Control and Prevention, Yueyang 414000, Hunan,China
  • Received:2014-04-09 Revised:2014-08-28 Online:2014-10-26 Published:2014-10-29

Abstract: AIM: To explore the impact of smoking, tea drinking and their interaction on susceptibility to tuberculosis. METHODS: A total of 427 tuberculosis patients and 410 healthy controls were recruited to participate in this case-control study. Self-developed questionnaire was used to collect data. RESULTS: Smoking was a risk factor against TB, with OR=1.621(1.152,2.301) , P<0.05. Tea drinking was a protective factor against TB, with OR=0.583(0.423,0.782), P<0.05. There were negative interactions between smoking and tea drinking, with a RERI of -0.24(-0.41,-0.07), P<0.05.CONCLUSION: Smoking could increase the risk of TB. Tea drinking could decrease the risk of TB. Tea drinking could soften the effect of smoking. Promoting the consumption of tea as daily drink among populations, particularly those with high TB risk, may reduce the incidence of TB in the population.

Key words: tuberculosis, smoking, tea drinking

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