Role of clinical pharmacists in the anti-infective therapy after anterior cruciate ligament reconstructions: an individualized medicine perspective

Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2017, Vol. 22 ›› Issue (2): 194-197.

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Role of clinical pharmacists in the anti-infective therapy after anterior cruciate ligament reconstructions: an individualized medicine perspective

YU Yang ^1,2, HE Jiake ², XIONG Aizhen², DING Nan¹

¹ Department of Pharmacy, the Affiliated Changhai Hospital of the Second Military Medical University, Shanghai 200433, China; ² Department of Pharmacy, the Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi, China

Received:2016-06-22 Revised:2016-08-15 Online:2017-02-26 Published:2017-03-02

Abstract

Abstract:

AIM: To explore the role of clinical pharmacists participating in the individualized anti-infective therapy after anterior cruciate ligament reconstruction. METHODS: Clinical pharmacists participated in the therapy for a patient with staphylococcus aureus infection after anterior cruciate ligament reconstruction. According to patient's condition, clinical pharmacist assisted physicians to formulate preliminary anti-infection plan.Embarking on drug sensitivity test, clinical pharmacist carried out individualized medication for patient by vancomycin serum concentration monitoring and population pharmacokinetic modeling. Close pharmaceutical care were conducted throughout the therapy. Moreover, clinical pharmacist assisted physicians to evaluate the therapeutic efficacy. RESULTS: According to vancomycin serum concentrations, clinical pharmacist suggested physician to change the anti-infection plan, and received a good therapeutic effect. CONCLUSION: Clinical pharmacists participate in the anti-infective therapy after anterior cruciate ligament reconstruction, and the designs of individualized dosing regimens contribute in the safety and effectiveness of drug use in patients with serious infection.

Key words: individualized medicine, anti-infective therapy, pharmacokinetic modeling, clinical pharmacists

CLC Number:

R969.3
R977

YU Yang, HE Jiake, XIONG Aizhen, DING Nan. Role of clinical pharmacists in the anti-infective therapy after anterior cruciate ligament reconstructions: an individualized medicine perspective[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2017, 22(2): 194-197.

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Role of clinical pharmacists in the anti-infective therapy after anterior cruciate ligament reconstructions: an individualized medicine perspective

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