关键词: 经鼻持续气道正压通气, 双相经鼻持续气道正压通气, 早产, 呼吸窘迫综合征, 新生儿

Abstract: Objective To compare the advantages and disadvantages of two modes as a primary mode of ventilation in premature infants with neonatal respiratory distress syndrome (RDS). Methods From January 2012 to December 2014,80 preterm infants with RDS who received in our hospital were randomly divided into two groups based on the primary mode of ventilation:nasal continuous positive airway pressure(NCPAP,n=40),bi-level positive airway pressure(SiPAP,n=40).The success rate of treatment and the incidence of different complications were compared. Results 1)Significantly,more infants in the SiPAP group remained extubated compared with those in the NCPAP group,whereas the success rate in SiPAP group was higher in NCPAP group(52% vs 26%,P<0.05).2)No significant difference in the complication was found between two groups(P>0.05). Conclusion The effect of nasal SiPAP for preterm infants with RDS appears to have greater advantage than that of NCPAP obviously,and without increasing the incidence of adverse events.

Key words: nasal continuous positive airway pressure, bi-level positive airway pressure, premature, respiratory distress syndrome, newborn