[1] 胡亚美,江载芳,申昆玲.诸福棠实用儿科学[M].8版.北京:人民卫生出版社,2013:469. [2] Ni Y,Wang Z,Ma L,et al.Pilose antler polypeptides ameliorate inflammation and oxidative stress and improves gut microbiota in hypoxic-ischemic injured rats[J].Nutr Res,2019,64:93-108. [3] Nonogaki K,Kaj T.Pharmacological stimulation of serotonin 5-HT1B receptors enhances increases in plasma active glucagon-like peptide-1 levels induced by dipeptidyl peptidase-4 inhibition independently of feeding in mice[J].Cell,2015,41(5):425-428. [4] Williams B,van Benschoten A,Cimermancic P,et al.Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine[J].Cell Host & Microbe,2014,16(4):495-503. [5] Latorre R,Sternini C,De Giorgio R,et al.Enteroendocrine cells:a review of their role in brain-gut communication[J].Neurogastroenterol Motil,2016,28(5):620-630. [6] Nicolas1 GR,Chang PV.Deciphering the chemical lexicon of host-gut microbiota interactions[J].Trends Pharmacol Sci,2019,40(6):430-445. [7] Deplancke B,Gaskins HR.Microbial modulation of innate defense:goblet cells and the intestinal mucus layer[J].Am J Clin Nutr,2001,73(Suppl 6):1131-1141. [8] Bansil R,Turner BS.The biology of mucus:composition,syn thesis and organization[J].Adv Drug Deliv Rev,2018,124:3-15. [9] Sgritta M,Dooling SW,Buffington SA,et al.Mechanisms underlying microbial-mediated changes in social behavior in mouse models of autism spectrum disorder[J].Neuron,2019,101(2):246-259. [10] Yuanyuan L,Benhua Z,Li Z,et al.Gut microbiota regulates mouse behaviors through glucocorticoid receptor pathway genes in the hippocampus[J].Transl Psychiatry,2018,8(1):187-189. [11] Patel M.Targeting oxidative stress in central nervous system disorders[J].Trends Pharmacol Sci,2016,37(9):768-778. [12] Smaga I,Niedzielska E,Gawlik M,et al.Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders.Part 2.Depression,anxiety,schizophrenia and autism[J].Pharmacol Rep,2015,67(3):569-580. [13] Dumitrescu L,Popescu-Olaru I,Cozma L,et al.Oxidative stress and the microbiota-gut-brain axis[J].Oxid Med Cell Longev,2018,2018:2406594. [14] Bonaz B,Bazin T,Pellissier S.The vagus nerve at the interface of the microbiota-gut-brain axis[J].Front Neurosci,2018,12:49. [15] Aridas J,Yawno T,Sutherland A,et al.Detecting brain injury in neonatal hypoxic ischemic encephalopathy:closing the gap between experimental and clinical research[J].Exp Neurol,2014,261:281-290. [16] Olatz A,álvarez A,Miren R,et al.Role of antioxidants in neonatal hypoxic-ischemic brain injury:new therapeutic approaches[J].Int J Mol Sci,2017,18(2):265. [17] Sanderson T,Reynolds C,Kumar R,et al.Molecular mechanisms of ischemia-reperfusion injury in brain:pivotal role of the mitochondrial membrane potential in reactive oxygen species generation[J].Mol Neurobiol,2013,47(1):9-23. [18] Yang Y,Zhang X,Cui Y,et al.Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways[J].Neurosci Lett,2014,568:44-49. [19] Fanaei H,Karimian S,Sadeghipour R,et al.Testosterone enhances functional recovery after stroke through promotion of antioxidant defenses,BDNF levels and neurogenesis in male rats[J].Brain Res,2014,1558:74-83. [20] Kim H,Leeds P,Chuang M,The HDAC inhibitor,sodium butyrate,stimulates neurogenesis in the ischemic brain[J].J Neurochem,2009,110(4):1226-1240. [21] Russell WR,Hoyles L,Flint HJ,et al.Colonic bacterial metabolites and human health[J].Current Opinion in Microbiology,2013,16(3):246-254. [22] Kelly C,Zheng L,Campbell E,et al.Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function[J].Cell Host & Microbe,2015,17(5):662-671. [23] Khan JY,Black SM.Developmental changes in murine brain antioxidant enzymes[J].Pediatr Res,2003,54(1):77-82. [24] Vadder F,Kovatcheva-Datchary P,Goncalves D,et al.Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits[J].Cell,2014,156(1-2):84-96. [25] Beaumont M,Andriamihaja M,Lan A,et al.Detrimental effects for colonocytes of an increased exposure to luminal hydrogen sulfide:The adaptive response[J].Free Radic Biol Med,2016,93:155-164. [26] Wu T,Yang L,Jiang J,et al.Chronic glucocorticoid treatment induced circadian clock disorder leads to lipid metabolism and gut microbiota alterations in rats[J].Life Sci,2018,192:173-182. [27] Watkins C,Murphy K,Yen S,et al.Effects of therapeutic hypothermia on the gut microbiota and metabolome of infants suffering hypoxic-ischemic encephalopathy at birth[J].J Biochem Cell Biol,2019,26:105550. [28] Nicolas GR,Chang PV.Deciphering the chemical lexicon of host-gut microbiota interactions[J].Trends Pharmacol Sci,2019,40(6):430-445. |