早产儿神经发育特点及临床诊疗进展

doi:10.11852/zgetbjzz2020-0849

中国儿童保健杂志 ›› 2021, Vol. 29 ›› Issue (8): 877-880.DOI: 10.11852/zgetbjzz2020-0849

早产儿神经发育特点及临床诊疗进展

王华倩, 姚宝珍

武汉大学人民医院儿科,湖北武汉 430000

收稿日期:2020-05-08 修回日期:2020-07-02 发布日期:2021-08-24 出版日期:2021-08-10
通讯作者: 姚宝珍,E-mail:professoryao@aliyun.com
作者简介:王华倩(1993-),女,湖北人,在读研究生,主要研究方向为小儿神经系统疾病。
基金资助:
武汉大学医学腾飞计划(TFLC2018001)

Progress of neurodevelopmental characteristics and clinical diagnosis and treatment in premature infants

WANG Hua-qian, YAO Bao-zhen

Department of Pediatrics,Renmin Hospital of Wuhan University,Wuhan,Hubei 430000,China

Received:2020-05-08 Revised:2020-07-02 Online:2021-08-10 Published:2021-08-24
Contact: YAO Bao-zhen, E-mail: professoryao@aliyun.com

摘要/Abstract

摘要： 随着医疗水平的进步,早产儿的存活率不断增加,但幸存的早产儿因各器官系统发育不完善,更易受到外界不良因素的影响,所面临的各种生后并发症的风险更大,特别是神经发育损伤,如脑性瘫痪、认知障碍、自闭症及执行功能障碍等,给家庭、社会及卫生系统带来沉重的负担。本文通过对早产儿神经发育特点、神经发育评估方法以及早期干预措施进行系统综述,为临床早期准确识别有神经系统损伤的早产儿、并对不同早产儿进行个体化的早期干预训练提供依据,以期改善早产儿的预后。

关键词: 早产儿, 神经发育, 神经发育评估, 早期干预

Abstract: With the improvement of medical treatment level, the survival rate of premature infants is continuously increasing.However, the surviving premature infants are more vulnerable to external adverse factors due to the imperfect development of various organs and systems, and face greater risks of various complications, especially neurodevelopmental injuries, such as cerebral palsy, cognitive disorders, autism and executive dysfunction, which bring heavy burdens to families, society and health systems.In this paper, the neurological development characteristics, neurological development assessment methods and early intervention measures of premature infants are systematically reviewed, so as to provide basis for clinical early and accurate identification of premature infants with neurological damage and individualized early intervention training for different premature infants, thereby improving the prognosis of premature infants.

Key words: premature infants, neurological development, neurological development assessment, early intervention

中图分类号:

R722.6

王华倩, 姚宝珍. 早产儿神经发育特点及临床诊疗进展[J]. 中国儿童保健杂志, 2021, 29(8): 877-880.

WANG Hua-qian, YAO Bao-zhen. Progress of neurodevelopmental characteristics and clinical diagnosis and treatment in premature infants[J]. Chinese Journal of Child Health Care, 2021, 29(8): 877-880.

参考文献

[1] World Health Organization.Born too soon: the global action reporton preterm birth [R].Geneva: WHO, 2012.
[2] Laptook AR.Neurologic and metabolic issues in moderately preterm, late preterm, and early term infants[J].Clin Perinatol, 2013,40 (4):723-738.
[3] Jiang ZD.A Longitudinal study of brainstem auditory response from birth to late term in late preterm babies and abnormal findings in high-risk babies[J].J Perinat Med,2015,43 (6):769-776.
[4] 黄艳梅.早产儿及足月儿颅脑CT的影像表现[J].实用医学影像杂志,2017,18(4):357-358.
[5] 吴宏伟,刘刚,王伟,等.早产儿脑发育过程中振幅整合脑电图的变化[J].中华实用儿科临床杂志,2017,32(2):109-111.
[6] Bulut C,Gürsoy T,Oval F.Short-term outcomes and mortality of late preterm infants[J].Balkan Med J,2016, 33 (2):198-203.
[7] Gulati S,Sondhi V.Cerebral palsy: an overview[J].Indian J Pediatr, 2018,85 (11):1006-1016.
[8] Hirvonen M,Ojala R,Korhonen P,et al.Cerebral palsy among children born moderately and late preterm[J].Pediatrics,2014,134 (6):e1584-1593.
[9] Pugliese M, Rossi C,Guidotti I,et al.Preterm birth and developmental problems in infancy and preschool age part II: cognitive, neuropsychological and behavioural outcomes[J].J Matern Fetal Neonatal Med,2013,26 (16):1653-1657.
[10] Sucksdorff M,Lehtonen L,Chudal R,et al.Preterm birth and poor fetal growth as risk factors of attention-deficit/hyperactivity disorder[J].Pediatrics, 2015,136(3):e599-608.
[11] Schieve LA,Tian LH,Rankin K,et al.Population impact of preterm birth and low birth weight on developmental disabilities in US children[J].Ann Epidemiol,2016,26 (4):267-274.
[12] Burnett AC,Anderson PJ,Lee KJ,et al.Trends in executive functioning in extremely preterm children across 3 birth eras[J].Pediatrics,2018,141 (1):e20171958.
[13] Woythaler M.Neurodevelopmental outcomes of the late preterm infant[J].Semin Fetal Neonatal Med,2019,24 (1):54-59.
[14] 胡斌,王成举,常琴, 等.不同胎龄早产儿Gesell发育量表的回顾性分析[J].中国妇幼健康研究,2018,29(9):1067-1070.
[15] 孙思媛,高雪婷,肖琳, 等.晚期早产儿160例Gesell婴幼儿智能测评研究[J].陕西医学杂志,2019,48(9):1171-1174.
[16] Cheong JL,Doyle LW,Burnett AC,et al.Association between moderate and late preterm birth and neurodevelopment and social-emotional development at age 2 years[J].JAMA Pediatr, 2017,171 (4):e164805.
[17] Brown N,Spittl A.Neurobehavioral evaluation in the preterm and term infant[J].Curr Pedia,2014,10 (1):65-72.
[18] 张腾伟,董海鹏,周卓妍, 等.婴幼儿神经发育评估方式的研究进展[J].中国妇幼健康研究,2016,27(12):1546-1548.
[19] 王成举,胡斌,张雨平.早产儿神经学评估工具研究进展[J].中国儿童保健杂志,2018,26(2):163-166.
[20] 黄彩虹,刘小红.早期综合干预对脑损伤早产儿神经系统发育影响的临床研究[J].中国实用神经疾病杂志,2016,19(5):80-81.
[21] 马丹,李娜,王秋, 等.感觉统合训练在高危早产儿早期干预中的疗效分析研究[J].中国全科医学,2018,21(32):4028-4031.
[22] Tekin T,Kavlak F,Cavlak U,et al.Effectiveness of neuro-developmental treatment (bobath concept) on postural control and balance in cerebral palsied children[J].J Back Musculoskelet Rehabil,2018,31 (2):397-403.
[23] 李娜,康琳敏,王秋,等.高危早产儿早期神经发育疗法干预的疗效分析[J].四川大学学报(医学版),2013,44(2):287-290.
[24] Modesto IF,Avelar AFM,Pedreira MDLG,et al.Effect of sleeping position on arousals from sleep in preterm infants[J].J Spec Pediatr Nurs,2016,21 (3):131-138.
[25] 汤晓丽,顾莺.新型体位辅助用具对早产儿早期神经行为发育影响的研究[J].护理学杂志,2018,33(1):18-21.
[26] 裴景君.母乳营养成分与早产儿脑发育的研究进展[J].中国当代儿科志,2019,21(6):607-612.
[27] Boundy EO,Dastjerdi R,Spiegelman D,et al.Kangaroo mother care and neonatal outcomes: a meta-analysis[J].Pediatrics,2016,137 (1):e20152901.
[28] 杨莲,钟秋莲.袋鼠式护理对早产儿综合发育的影响[J].当代护士(中旬刊),2020,27(1):73-75.
[29] 邓宜雅,高子莹,黄辉文, 等.保持"宫内姿势"对早产儿神经系统发育的干预研究[J].岭南急诊医学杂志,2019,24(4):403-404.
[30] 栗红,胡晶,阴怀清, 等.非营养性吸吮在促进危重早产儿生长发育中的作用研究[J].中国药物与临床,2018,18(10):1855-1856.

早产儿神经发育特点及临床诊疗进展

Progress of neurodevelopmental characteristics and clinical diagnosis and treatment in premature infants

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

[1]	张丹, 张军, 杨钰荣, 曹咪, 闫敬敏, 朱璐阳. 肠道菌群与早产儿脑发育及神经认知行为关系的研究[J]. 中国儿童保健杂志, 2023, 31(7): 756-759.
[2]	冯骁, 陈凌, 赵红缨, 黄蕊, 林辰曦, 庄丽娟. 不同脐带挤压方式对极早产儿结局的影响[J]. 中国儿童保健杂志, 2023, 31(7): 794-798.
[3]	李嘉, 张延赤. 维生素D受体基因多态性及维生素D水平与神经发育障碍关系的研究进展[J]. 中国儿童保健杂志, 2023, 31(5): 516-520.
[4]	刘佳敏, 赵莎, 钟燕. 外泌体与儿童神经精神障碍的研究进展[J]. 中国儿童保健杂志, 2023, 31(5): 521-525.
[5]	郑亭玉, 张春宇, 杨飞, 郑芳, 张梦霞, 夏露萍, 徐孙超. 营养支持小组管理模式对早产儿生长发育及免疫功能的影响[J]. 中国儿童保健杂志, 2023, 31(5): 555-558.
[6]	王晓庆, 刘九月, 姚光. 小于胎龄儿早期脑发育及18~24月龄时神经发育状况的前瞻性队列研究[J]. 中国儿童保健杂志, 2023, 31(4): 353-358.
[7]	夏正龙, 宋燕燕. 支气管肺发育不良早产儿神经发育研究[J]. 中国儿童保健杂志, 2023, 31(4): 390-394.
[8]	李静兰, 孙文强, 朱雪萍. 早产儿支气管肺发育不良相关预测模型研究[J]. 中国儿童保健杂志, 2023, 31(4): 395-398.
[9]	王娜, 李晓莺. 早产儿神经发育评估的进展[J]. 中国儿童保健杂志, 2023, 31(4): 404-407.
[10]	任力, 黑明燕, 齐宇洁, 靳绯, 翁景文, 董世霄, 沈艳华, 姜敏. 早产儿喂养对坏死性小肠结肠炎发病的影响[J]. 中国儿童保健杂志, 2023, 31(4): 438-441.
[11]	陈峰, 张宇. 多胞胎和单胞胎早产儿神经发育的回顾性研究[J]. 中国儿童保健杂志, 2023, 31(4): 451-456.
[12]	王晶, 项思嘉, 鲁莹, 杨蕾, 胡小沙, 钱君, 池霞, 张敏. 早产儿3周岁体格生长及体成分分析[J]. 中国儿童保健杂志, 2023, 31(4): 457-460.
[13]	郑水英, 罗艳赟. 早产儿喂养不耐受的临床表现及相关影响因素[J]. 中国儿童保健杂志, 2023, 31(4): 461-464.
[14]	林欢喜, 刘潘婷, 童梅玲, 池霞, 钱君, 洪琴. 父母介导的干预在孤独症谱系障碍治疗中应用效果的Meta分析[J]. 中国儿童保健杂志, 2023, 31(3): 304-310.
[15]	黄亨烨, 于广军. 婴幼儿早期神经发育评估诊断量表的综述[J]. 中国儿童保健杂志, 2023, 31(2): 162-166.