中国儿童保健杂志 ›› 2014, Vol. 22 ›› Issue (2): 172-174.

• 临床研究与分析 • 上一篇    下一篇

十堰市城区3~6岁儿童血清维生素A水平与影响因素分析

曾婧1, 辜伟伟2, 李兆林2, 齐运平2, 姚平3, 杨雪锋3, 孙秀发3   

  1. 1 武汉科技大学医学院公共卫生学院, 湖北 武汉 430065;
    2 十堰市疾病预防控制中心, 湖北 十堰 442000;
    3 华中科技大学同济医学院营养与食品卫生系, 湖北 武汉 430030
  • 收稿日期:2013-06-18 发布日期:2014-02-10 出版日期:2014-02-10
  • 作者简介:曾婧(1977-), 女, 湖北人, 副教授, 医学博士, 主要研究方向为儿童营养保健。
  • 基金资助:
    国家十一五科技支撑计划项目(2008BAI58B03)

Serum vitamin A levels and its influence factors of children aged 3~6 years old in urban area in Shiyan.

ZENG Jing1, GU Wei-wei2, LI Zhao-lin2, QI Yun-ping2, YAO Ping3, YANG Xue-feng3, SUN Xiu-fa3.   

  1. (1 School of Public Health, Wuhan University of Science and Technology, Wuhan, Hubei 430065, China; 2 Center for Disease Control of Shiyan City, Shiyan, Sichuan 442000, China; 3 Department of Nutrition and Food Hygiene, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China)
  • Received:2013-06-18 Online:2014-02-10 Published:2014-02-10

摘要: 目的 了解十堰市城区3~6岁儿童维生素A营养状况及其影响因素, 为制订干预对策提供依据。方法 抽取十堰市城区某幼儿园3~6岁儿童225名, 通过问卷调查、体格检查和实验室检查了解被调查儿童的家庭情况、饮食习惯、生长发育情况及健康状况等。以高效液相色谱法测定血清视黄醇的含量。结果 205名儿童的血清维生素A均值为(1.27±0.40)μmol/L, 亚临床维生素A缺乏(subclinical vitamin A deficiency, SVAD)患病率为5.37%, 可疑SVAD患病率为21.46%。单因素分析发现年龄、母亲的文化程度、家庭年总收入、家庭年饮食消费开支、食欲、血红蛋白、脂肪吸收试验、营养素补充剂服用情况有统计学意义。多因素分析发现只有脂肪吸收试验有统计学意义, 脂肪吸收试验阳性组SVAD患病率明显高于阴性组。结论 SVAD是十堰市城区幼儿园集体儿童尚存的营养问题之一, 应加强幼儿园儿童SVAD和可疑SVAD的防治工作。

关键词: 维生素A缺乏, 影响因素, 儿童

Abstract: Objective To study the current status of serum vitamin A level and its influence factors of children in urban area in Shiyan city. Methods 225 children aged 3~6 years old from kindergarten in the urban area were selected.The data of children's family situation, eating habits, growth and development, and children's health status were collected through the questionnaire survey, physical examination and laboratory examination.A method of reversed-phase high performance liquid chromatography was used to determine the level of serum retinol. Results The serum retinol concentration was (1.48±0.52)μmol/L, The prevalence of subclinical vitamin A deficiency (SVAD) was 5.37%, and the prevalence of suspicious SVAD was 21.5%.Univariate analysis showed that age, mother's education level, household income, household expenditure on food, appetite, hemoglobin, fat absorption test, whether taking nutritional supplements were statistically significant.Only fat absorption test was found to be statistically significant after the multivariate analysis, the positive group had higher SVAD prevalence than that of negative group. Conclusion SVAD is still a nutrition problem in kindergartens in urban area in Shiyan city, the work of prevention and control SVAD and suspicious SVAD should be strengthened in kindergarten.

Key words: vitamin A deficiency, influence factors, children

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