Abstract: Objective To describe the incidence of intrauterine growth restriction (IUGR) and extrauterine growth restriction (EUGR) in premature infants from NICU in the affiliated children's Hospital of Soochow University hospital and analyze the correlated factors with EUGR. Methods Data of the premature infants hospitalized from NICU in our hospital were reviewed.The incidences of IUGR and EUGR were assessed and the correlated risk factors was analyzed. Results The subject included 126 premature infants.The incidences of IUGR and EUGR were 29.37% and 27.78% by weight,of which the incidence rate of EUGR in SGA preterm children was 54.05%.Logistic regression analysis showed the risk factors associated with EUGR including small gestational age at birth,low birth weight,and merge complications. Conclusion The IUGR,EUGR incidence rates of preterm children are still high.It will be better to take early positive nutritional support,prevention and treatment of common complications in preterm children to reduce the incidence of EUGR and improve their quality of life.

Key words: premature infants, small for gestational age, extrauterine growth restriction, incidence of intrauterine growth restriction

摘要： 目的 评价苏州大学附属儿童医院新生儿重症监护室(NICU)早产儿出生时宫内生长发育迟缓(intrauterine growth restriction,IUGR)和出院时宫外生长发育迟缓(extrauterine growth restriction,EUGR)的发生比例,并评估EUGR的危险因素。方法 对本院NICU126例早产儿病例资料进行回顾性分析,对其宫内、宫外生长发育迟缓的发生比例进行统计,并通过Logistic回归分析对相关危险因素进行评估。结果 126例早产儿出生时IUGR的比例为29.37%,出院时EUGR的比例占27.78%,其中SGA早产儿EUGR发生比例达54.05%。Logistic回归分析表明,与EUGR有关的高危因素包括出生胎龄小、低出生体重以及合并并发症等。结论 NICU中早产儿IUGR、EUGR的发生比例仍较高。对其采取正确的、积极的早期营养支持,并防治早产儿常见合并症,对减少EUGR的发生、提高其生存质量意义重大。

关键词: 早产儿, 小于胎龄儿, 宫外生长发育迟缓, 宫内生长发育迟缓