journal1 ›› 2015, Vol. 23 ›› Issue (3): 319-320.DOI: 10.11852/zgetbjzz2015-23-03-31

Previous Articles     Next Articles

Antenatal and postnatal situation survey of 202 cases children with autism and its influential factors in Shenzhen city

GAO Jian,SONG Hui,DUAN Yong-heng,JIA Qiu-li,LIN Sheng,LIU Zhi-qiang,ZHANG Ling-hua,XIE Li-chun,ZENG Xu-chun,GU Xue-ying,DUAN Shan   

  1. Laboratory of Medical Genetics,Shenzhen Research Institute of Population and Family Planning,Shenzhen,Guangdong 518040,China
  • Received:2014-08-04 Online:2015-03-10 Published:2015-03-10
  • Contact: DUAN Shan,



  1. 深圳市人口和计划生育科学研究所医学遗传实验室,广东 深圳 518040
  • 通讯作者: 段山,
  • 作者简介:高建(1983-),女,湖北人,实验员,工程师,硕士研究生,主要研究方向为儿童孤独症的分子遗传机制。
  • 基金资助:

Abstract: Objective To investigate the influential factors of children with autism. Method The data of 202 children with autism were analyzed with SPSS18.0 software. Results The sex ratios of male:female was 6.48∶1;The reproductive age of father and mother was (30.76±4.09)y and (27.67±3.55)y respeatively,up to 93.9% father's age was beyond 26,also,34.0% of the mother of autistic reported who had diseases during the gestation period;For the following reasons,the selection of cesarean section accounted for 55.2%,such as fetal distress(20.0%),failed trial of labor (13.3%) and amniotic fluid abnormality(12.2%),and so on;During infancy,43.30% of the autistics children had suffered with illness,among which pathological neonatal jaundice accounted for 38.1%. Conclusion Fetal distress,pathological neonatal jaundice and advanced paternal age are all may be one of the influential factors of autism.

Key words: autism, fetal distress, pathological neonatal jaundice, influential factors

摘要: 目的 探讨儿童孤独症的影响因素,为孤独症的病因学研究提供基础参考依据。方法 采用SPSS 18.0软件对研究对象的资料进行汇总分析。结果 202例孤独症儿童中,男女比例为6.48∶1,父母亲的平龄育龄为(30.76±4.09)岁和(27.67±3.55)岁,其中父亲年龄≥26岁的比例高达93.9%,有34.0%的母亲孕期曾患病;有55.2%的儿童以剖宫产方式出生,原因主要有胎儿窘迫(20.0%)、试产不成功(13.3%)和羊水异常(12.2%)等;儿童在婴儿期曾经患病的比例为43.3%,其中患病理性新生儿黄疸者高达38.1%。结论 胎儿窘迫、病理性新生儿黄疸以及偏大的父亲年龄可能是诱发孤独症的影响因素。

关键词: 儿童孤独症, 胎儿窘迫, 病理性新生儿黄疸, 影响因素

CLC Number: