Abstract: Objective To assess the cognitive function and characteristics of children with epilepsy by using Wechsler Intelligence Scale for Children,Fourth Edition (WISC-Ⅳ),and to analyze the influencing factors of cognitive function in epilepsy children . Method Totally 45 children with epilepsy were screened according to the International League Against Epilepsy (ILAE) criteria from August 2016 to October 2017,and 36 matched healthy children were selected as control group.Cognitive function assessment was performed on all children with WISC-Ⅳ.Also,the characteristics and effects of cognitive function in epilepsy children were analyzed. Results The WISC-Ⅳ test showed that epilepsy group scored significantly lower in the total IQ,four indexes,and subtests than control group,and showed poorer performance in terms of cognitive efficiency(t=6.008,P<0.05).Parental education,medication time,frequency of seizures,and education forms could affect the cognitive efficiency of epilepsy children.Moreover,fathers′ education was a high-risk factor. Conclusions The application of WISC-Ⅳ can intuitively identify the advantages and disadvantages of cognitive function in epilepsy children,thereby providing evidence for early cognitive intervention.

Key words: epilepsy children, Wechsler Intelligence Scale for children,Fourth Edition, cognitive efficiency, cognitive assessment

摘要： 目的 应用韦氏儿童智力量表第四版(WISC-Ⅳ)评估癫痫儿童的认知功能及其特征,分析癫痫儿童认知功能的影响因素。方法 按照国际抗癫痫联盟(ILAE)标准于2016年8月-2017年10月筛选45例癫痫患儿,选取36例匹配的健康儿童作对照组,用WISC-Ⅳ对所有儿童进行认知评估;分析癫痫儿童认知功能特征及影响因素。结果 从WISC-Ⅳ测验结果中得出,癫痫组在总智商、四个指数、分测验上得分均较对照组低,并在认知效率方面表现弱势,差异具有统计学意义(t=6.008,P<0.05);父母文化程度、服药时间、发作频率及教育形式可影响癫痫儿童认知效率,其中父亲文化程度是高危因素。结论 应用WISC-Ⅳ能直观发现癫痫儿童认知功能的优弱项,并为早期认知干预提供依据。

关键词: 癫痫儿童, 韦氏儿童智力量表第四版, 认知效率, 认知评估