Abstract: Objective To establish strategies for preventing and managing hypoglycemia in children and adolescents with type 1 diabetes, in order to provide a clinical practice basis for reducing the incidence of hypoglycemia and optimizing comprehensive blood sugar management. Methods All domestic and foreign evidence on the prevention and management of hypoglycemia in children was retrieved until August 2023, including clinical practice guidelines, evidence summaries, best practice information books, expert consensus, systematic reviews, and original studies. Results This study included 9 articles, comprising 3 practical guidelines, 4 expert consensus articles, 1 clinical decision, and 1 evidence summary, covering 9 aspects ranging from hypoglycemia identification, risk factors, blood sugar monitoring, insulin treatment plans, health education, diet, exercise, and psychological support. It presents a total of 34 pieces of evidence, synthesizing the best evidence from both domestic and international sources on hypoglycemia prevention strategies for children and adolescents with type 1 diabetes. Conclusion Based on the latest evidence from domestic and global sources, this study systematically illustrates prevention strategies for hypoglycemia in children and adolescents with type 1 diabetes, providing comprehensive evidence and a reliable theoretical basis for raising clinical caregivers' awareness of hypoglycemia prevention, reducing the risk of hypoglycemia occurrence, and constructing a systematic hypoglycemia prevention and control strategy.

Key words: type 1 diabetes, hypoglycemia, prevention, children

摘要： 目的 构建1型糖尿病儿童/青少年低血糖预防与管理策略,为降低低血糖发生率、优化血糖综合管理提供临床实践依据。方法 检索建库至2023年8月国内外关于儿童1型糖尿病低血糖预防管理的所有证据,包括临床实践指南、证据总结、最佳实践信息册、专家共识、系统评价及原始研究。结果 本研究共纳入9篇文献,包括3篇实践指南,4篇专家共识,1篇临床决策,1篇证据总结,从低血糖识别、危险因素、血糖监测目标、血糖监测、胰岛素治疗方案、健康教育、饮食、运动、心理支持9个方面,共34条证据进行介绍,综合了国内外对1型糖尿病儿童/青少年低血糖预防策略的最佳证据。结论 本研究基于国内外最新证据,系统阐述了1型糖尿病儿童/青少年低血糖的预防策略,证据内容全面,为提高临床护理人员低血糖防范意识、降低低血糖发生风险,构建系统的低血糖预防控制策略提供可靠的理论依据。

关键词: 1型糖尿病, 低血糖, 预防, 儿童