Research progress in the effects of the main active ingredients of breast milk on the intestinal and immune functions of infants

doi:10.11852/zgetbjzz2023-0907

Abstract

Abstract: Gut microbiome plays an important role in maintaining lifelong health. Infancy is a critical period for the establishment of gut microbiota, which is influenced by many factors, including delivery methods, antibiotics, and feeding mode. Human milk contains a variety of bioactive factors, such as human milk oligosaccharide, secretory immunoglobulin, and human milk microbiota, which play important roles in the establishment and stability of newborn microbiota. This article presents the latest research progress on the effects of the aforementioned bioactive factors in breast milk on the colonization and development of infant microbiota, and explains how these substances affect immune function through intestinal bacteria.

Key words: breast milk, infant, bioactive substances, gut microbiota, immunity

摘要： 肠道微生物组在维持一生健康方面发挥着重要作用。婴儿时期是肠道菌群建立的关键时期,会受到多种因素影响,包括分娩方式、抗生素和喂养方式等。母乳中含有多种生物活性因子,如母乳低聚糖、分泌型免疫球蛋白、母乳微生物群等,对婴儿微生物群的建立和稳定发挥了重要作用。本文将综合阐述上述母乳生物活性因子影响婴儿微生物群定植和发展的最新研究进展,及上述物质如何通过肠道细菌影响免疫功能。

关键词: 母乳, 婴儿, 生物活性物质, 肠道菌群, 免疫

CLC Number:

R174.4

LYU Lina, ZHU Bingquan. Research progress in the effects of the main active ingredients of breast milk on the intestinal and immune functions of infants[J]. Chinese Journal of Child Health Care, 2024, 32(4): 424-428.

吕丽娜, 朱冰泉. 母乳主要活性成分对婴儿肠道及免疫功能影响的研究进展[J]. 中国儿童保健杂志, 2024, 32(4): 424-428.

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