Abstract: Objective To understand the situation of pregnant women Perfluorinated compounds(PFCs) occupational exposure, and to analyze the effects of 0~1 years old infants' physical and mental development when their mother subjected to the influence of PFCs. Method Pilot investigation was used to select 0~1 years old infants who went to a place for examination, and to collect infants' physical and mental development status and their mother' situation of PFCs occupational exposure with a self-designed questionnaire and Denver Development Screen Test (DPST). Results The survey of women's career related to PFCs occupational exposure factor accounted for 7.4%.The difference of the infants' physical development index, whose mother engaged in the career related to printing, leather and its products or other career were statistically significant, but the difference of the infants' mental development index was not statistically significant(P＞0.05).However, the survey Results showed that there were 60% infants that assessment result of mental development was suspicious, and their mother engaged in the career related to clothing and textile;there were 50% infants that assessment result of mental development was suspicious, and their mother engaged in the career related to boiler and coal-fired. Conclusion Women of childbearing age should avoid contact with PFCs, and those who engaged in the career related to PFCs should keep away from the environment as soon as possible.

Key words: Perfluorinated compounds, infant, physical and mental development

摘要： 目的 了解孕期妇女全氟化合物的职业接触情况, 并分析孕期妇女在受到全氟化合物的影响后与0~1岁婴儿生理心理发展有无关联性, 为妇女的孕期保健和婴儿正常身心发展指导提供参考依据。方法 采用试点调查的方法选取某地医院体检0~1岁婴儿, 用自编调查问卷和丹佛发育筛查量表收集婴儿母亲全氟化合物的职业性接触相关信息及婴儿生理心理发育状况。结果 本次调查的妇女职业中与全氟化合物职业接触因子相关的占7.4%。且从事与印刷品、皮革及其制品相关工作妇女的0~1岁婴儿, 与没有从事相关工作的0~1岁婴儿的各项生理发育指标差异具有统计学意义;与婴儿的心理发育无显著相关性(P＞0.05), 但调查结果显示母亲职业与服装、纺织品相关的婴儿, 其心理发育评定结果为可疑的占60%, 母亲职业与烧锅炉、燃煤相关的婴儿, 其心理发育评定结果为可疑的占50%。结论 育龄妇女应避免全氟化合物的接触, 对于从事与其有关的职业, 应及早脱离接触环境。

关键词: 全氟化合物, 婴儿, 生理心理发展