Study on the incidence and risk factors of small for gestational age infant with single fetus and live births

doi:10.11852/zgetbjzz2019-0431

Abstract

Abstract: Objective To investigate the incidence of small for gestational age(SGA) in Huadu district of Guangzhou,and to analyze its risk factors,so as to provide evidence for prevention on SGA. Methods Totally 3 509 singleton live births in Guangzhou Huadu District Maternal and Child Health Hospital were enrolled in this study from October 2017 to September 2018.Data on neonatal gestational age,birth weight,maternal general condition,nutrient intake during pregnancy,environmental exposure,lifestyle behavior and so on were collected,the incidence of SGA was calculated,and the influencing factors were analyzed. Results The incidence of SGA infants was 8.78%(308/3 509).Multivariate Logistic analysis showed that oligoamnion(OR=3.275,95%CI:2.043-5.250),maternal age over 35 years old(OR=1.712,95%CI: 1.216-2.411),non-registered pregnant women(OR=1.620,95%CI:1.158-2.266;OR=1.660,95%CI:1.126-2.448 ),low weight prepregnancy(OR=2.300,95%CI:1.515-3.827),Low weight gain during pregnancy(OR=2.286,95%CI:1.572-3.326),frequent exposure to second-hand smoking(OR=5.690,95%CI:1.401~23.104) were risk factors for SGA(P＜0.05).Gestational diabetes mellitus(OR=0.674,95%CI:0.456-0.996), more gravidity(OR=0.802,95%CI:0.716-0.897) were protective factors for SGA(P＜0.05). Conclusions The occurrence of SGA is related to many factors,which is the result of the combination of social factors,environmental factors and pregnancy complications.To prevent the occurrence of SGA,comprehensive interventions are needed.

Key words: small for gestational age, incidence, risk factor

摘要： 目的了解广州花都区小于胎龄儿发生率并分析其影响因素,为预防小于胎龄儿的发生提供科学依据。方法于2017年10月-2018年9月在广州市花都区妇幼保健院招募住院分娩孕妇进入研究。根据纳入排除标准,共有3 509名单胎活产儿纳入到本次研究。收集新生儿胎龄、出生体重、产妇的一般情况、孕期营养素摄入、环境接触、生活行为方式等信息,计算小于胎龄儿的发生率,并对影响因素进行分析。结果小于胎龄儿的发生率为8.78%(308/3 509)。羊水过少(OR=3.275,95%CI:2.043~5.250)、孕妇年龄≥35岁(OR=1.712,95%CI: 1.216~2.411),非广州市户籍(OR=1.620,95%CI:1.158~2.266;OR=1.660,95%CI:1.126~2.448 )、孕前低体重(OR=2.300,95%CI:1.515~3.827)、孕期增重不足(OR=2.286,95%CI:1.572~3.326)、孕期经常接触烟雾(OR=5.690,95%CI:1.401~23.104)是SGA发生的危险因素(P＜0.05)。妊娠糖尿病(OR=0.674,95%CI:0.456~0.996)、孕次多(OR=0.802,95%CI:0.716~0.897)的产妇小于胎龄儿的发生率较低。结论小于胎龄儿的发生与多种因素有关,是社会因素、环境因素、妊娠并发症共同作用的结果。要防止SGA的发生,需要制定一个综合的干预措施。

关键词: 小于胎龄儿, 发生率, 影响因素

CLC Number:

R722.6

CHEN Gan-ne, WU Yong, HUANG Wei-wen, LIU Yun-hui, HUANG Wan-ping. Study on the incidence and risk factors of small for gestational age infant with single fetus and live births[J]. journal1, 2019, 27(10): 1105-1108.

陈甘讷, 吴泳, 黄伟雯, 刘云辉, 黄婉平. 单胎活产儿小于胎龄儿发生率及影响因素分析[J]. 中国儿童保健杂志, 2019, 27(10): 1105-1108.

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