Abstract: Objective To examine infants sleep patterns in Shunyi District, in order to provide reference for giving early sleep guidance to parents. Methods The prospective cohort study enrolled 220 healthy infants from China Longitudinal Environmental, Genetic and Economic Cohort (CHALLENGE) in Shunyi District of Beijing, and the infants were followed up at the age of 42 days, 3 and 6 months old.The demographic data of infants were collected, and the Brief Infant Sleep Questionnaire (BISQ) was used to evaluate the sleep patterns and sleep disorders of infants. Results 0- to 6-month-old infants changed significantly in sleep duration time of day and night.The daytime sleep duration decreased significantly from (6.0±2.3)h on 42 days old to (3.8±1.5)h on 6 months old.Nocturnal sleep duration increased significantly from (6.9±2.2)h on 42 days old to(8.1±2.3)h on 6 months old.Multiple linear regression analysis showed nighttime awakenings of 42-day and 6-month-old infants were positively correlated with feeding asleep patterns (β=0.69,0.80,P<0.001). Conclusions The sleep patterns of infants changes significantly at 6 months old after birth, and the way of feeding asleep is significantly related to the number of nighttime awakenings.Parents should make appropriate response to reduce the occurrence of infant sleep problems.

Key words: infants, sleep, feeding asleep, nighttime awakening, cohort study

摘要： 目的 分析顺义区0~6月龄婴儿睡眠模式,为婴儿早期睡眠指导提供参考。方法 采用队列研究的方法,在顺义妇幼健康之约队列研究中招募220例健康新生儿,在42天、3月龄、6月龄进行随访,使用简明婴儿睡眠问卷(BISQ)评估婴儿睡眠模式和睡眠问题。结果 0~6月龄婴儿白天和夜晚睡眠时间变化显著,白天睡眠时间从42天(6.0±2.3)h逐渐下降至6月龄(3.8±1.5)h,夜晚睡眠时间从42天(6.9±2.2)h逐渐上升至6月龄(8.1±2.3)h。42天、6月龄婴儿夜醒次数与奶睡呈正相关(β=0.69、0.80,P<0.001)。结论 婴儿睡眠模式在生后6个月变化明显,奶睡的方式与夜醒次数明显相关,家长应采取正确的入睡方式以减少婴儿睡眠问题的发生。

关键词: 婴儿, 睡眠, 奶睡, 夜醒, 队列研究