journal1 ›› 2017, Vol. 25 ›› Issue (2): 158-160.DOI: 10.11852/zgetbjzz2017-25-02-14

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Early prediction and drug therapy of capillary leak syndrome in newborn

SHENG Li-juan,HUANG Wei-min   

  1. Neonatal Department,Nanfang Hospital of Southern Medical University,Guangzhou,Guangdong 510515,China
  • Received:2016-08-24 Online:2017-02-10 Published:2017-02-10
  • Contact: HUANG Wei-min,



  1. 广东省南方医科大学附属南方医院新生儿科,广东 广州 510515
  • 通讯作者: 黄为民,
  • 作者简介:盛丽娟(1988-),女,湖北人,硕士在读,新生儿专业,研究方向为早产儿综合管理。

Abstract: Capillary leak syndrome (CLS) is one of the common critical cases in NICU.Capillary leak syndrome has high mortality and complex clinical manifestation.It is often neglected due to other complications.Currently,there is no uniform diagnostic criteria.The diagnosis mainly base on clinical manifestation and laboratory examination.The therapeutic principles mainly include controlling the primary disease and fluid resuscitation.Common drugs include antibiotics,hydroxyethyl starch,albumin,blood products,vasoactive agent and so on.Understanding the pathogenesis and clinical manifestations and giving early intervention may improve the survival rate and prognosis of newborns with CLS.   

Key words: capillary leak syndrome, newborn, early prediction, drug therapy

摘要: 毛细血管渗漏综合征(CLS)是NICU常见的危重症之一,死亡率高,其临床表现复杂,分期界限模糊,常因其他合并症而易被忽视。目前尚无明确的诊断标准,主要根据临床表现及实验室检查来诊断。治疗原则主要包括控制原发疾病及液体复苏等,常用药物包括抗生素、羟乙基淀粉、白蛋白、血制品、血管活性药等。了解其发病机制及临床表现,通过早期预测,早期干预,对提高CLS患儿生存率和预后有重要意义。

关键词: 毛细血管渗漏综合征, 新生儿, 早期预测, 药物治疗

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