Abstract: Objective To compare effects of individualized health management and routine intervention on children with simple obesity for one year,and to explore a more effective intervention model for obese children. Methods A total of 130 simple obese children aged 3~8 were enrolled,and were randomly assigned to an individualized diet,exercise,behavioral intervention (individualized group) and general intervention (routine group).After one-year intervention,body mass index (BMI),waist circumference,body fat percentage,glucose and lipid metabolism and C-creative protein (CRP) were compared between two groups and body shape index of different genders,different places of study were compared before and after intervention among the individualized groups. Results After 1 year of intervention,the decrease of BMI,waist circumference,body weight and body fat percentage in the individual group was more obvious than those in the routine group (P<0.001).The height growth of the individualized group was higher than that of the routine group (P<0.001).The levels of fasting blood glucose,fasting insulin,LDL,TG,TC and CRP in the individual group were lower than those in the routine group (P<0.01),and HDL was higher than that in the routine group (P<0.01). Conclusion Individualized health management can effectively improve the body shape of simple obese children aged 3~8.Improving the levels of glucose,lipid metabolism and CRP is an effective intervention model for obese children.

Key words: individualized health management, childhood obesity, simple obesity, intervention, treatment

摘要： 目的 比较个体化健康管理与常规干预1年对单纯性肥胖儿童的效果,探究更为有效的肥胖儿童干预模式。方法 共入组3~8岁单纯性肥胖儿童130例,随机接受个体化的饮食、运动、行为干预(个体化组)与常规干预(常规组)。比较两组在干预1年后体质量指数(BMI)、腰围、体脂百分比等身体形态指标及糖脂代谢、C反应蛋白(CRP)等生化指标有无差异,比较个体化组中不同性别、不同学习地点肥胖儿童干预前后身体形态指标有无差异。结果 干预1年后,个体化组BMI、腰围、体重、体脂百分比的减少比常规组更明显(P值均＜0.001),身高增长高于常规组(P＜0.001);个体化组空腹血糖、空腹胰岛素、LDL、TG、TC、CRP均较常规组降低(P值均＜0.01),HDL较常规组升高(P＜0.01)。结论 个体化健康管理可有效改善3~8岁单纯性肥胖儿童的身体形态,改善糖脂代谢及CRP水平,是对肥胖儿童的一种有效干预模式。

关键词: 个体化健康管理, 儿童肥胖, 单纯性肥胖, 干预, 治疗