Chinese Journal of Child Health Care ›› 2024, Vol. 32 ›› Issue (4): 349-358.DOI: 10.11852/zgetbjzz2024-0279
• Consensus • Next Articles
Received:
2024-03-12
Revised:
2024-03-15
Online:
2024-04-10
Published:
2024-04-15
中华预防医学会儿童保健分会
CLC Number:
中华预防医学会儿童保健分会. 中国儿童维生素A、维生素D临床应用专家共识(2024)[J]. 中国儿童保健杂志, 2024, 32(4): 349-358.
[1] 赵丽云,丁钢强,赵文华.2015-2017年中国居民营养与健康状况监测报告[M].北京:人民卫生出版社,2022. [2] 田亭,张静娴,谢玮,等.2016-2017年江苏省6-17岁儿童青少年维生素A和维生素D营养状况[J].卫生研究,2023,52(6):930-935. [3] Chaudhry A,Hajat S,Rizkallah N,et al.Risk factors for vitamin A and vitamin D deficiencies in children younger than 5 years in the occupied Palestinian territory:A cross-sectional study[J].Lancet,2018,391(Suppl 2):3. [4] Chaudhry AB,Hajat S,Rizkallah N,et al.Risk factors for vitamin A and D deficiencies among children under-five in the state of Palestine[J].Confl Health,2018,12:13. [5] 中华预防医学会儿童保健分会.中国儿童维生素A、维生素D临床应用专家共识[J].中国儿童保健杂志,2021,29(1):110-116. [6] 安娜,赵宜乐,张古英,等.2010—2020年中国健康儿童维生素D水平的Meta分析[J].中国儿童保健杂志,2021,29(10):1109-1114. [7] 中国营养学会.中国居民膳食营养素参考摄入量(2023版)[M].北京:人民卫生出版社,2023. [8] Tanumihardjo SA.Vitamin A:Biomarkers of nutrition for development[J].Am J Clin Nutr,2011,94(Suppl 2):658-665. [9] Song P,Wang J,Wei W,et al.The prevalence of vitamin A deficiency in Chinese children: A systematic review and bayesian Meta-analysis[J].Nutrients,2017,9(12):1285. [10] 杨振宇.中国居民营养与健康状况监测报告(2010—2013)之九-中国0~5岁儿童营养与健康状况[M].北京:人民卫生出版社,2020. [11] Chen Q,Liu Y,Chen L,et al.Vitamin A levels among pre-school children of Central and Western China[J].Front Public Health,2021,9:694106. [12] Wu J,Wang HJ,Zhang X,et al.Vitamin A status and its hematological correlates among preschool children in Beijing,China[J].Asia Pac J Clin Nutr,2022,31(4):748-752. [13] 杨春,陈竞,云春凤,等.中国中小城市小学生维生素A缺乏和贫血现况调查[J].卫生研究,2016,45(3):489-491. [14] Munns CF,Shaw N,Kiely M,et al.Global consensus recommendations on prevention and management of nutritional rickets[J].J Clin Endocrinol Metab,2016,101(2):394-415. [15] 李娈娈,李晓南,贾飞勇,等.中国部分地区7岁以下儿童维生素D营养状况分析[J].中华儿科杂志,2022,60(5):413-420. [16] Pleiner J,Schaller G,Mittermayer F,et al.Intra-arterial vitamin C prevents endothelial dysfunction caused by ischemia-reperfusion[J].Atherosclerosis,2008,197(1):383-391. [17] Llesuy S,Milei J,Picone V,et al.Effect of vitamins A and E on ischemia-reperfusion damage in rabbit heart[J].Mol Cell Biochem,1995,145(1):45-51. [18] Mora JR,Iwata M,von Andrian UH.Vitamin effects on the immune system: Vitamins A and D take centre stage[J].Nat Rev Immunol,2008,8(9):685-698. [19] Biesalski HK.Vitamin D recommendations:Beyond deficiency[J].Ann Nutr Metab,2011,59(1):10-16. [20] Linday LA,Umhau JC,Shindledecker RD,et al.Cod liver oil,the ratio of vitamins A and D,frequent respiratory tract infections,and vitamin D deficiency in young children in the United States[J].Ann Otol Rhinol Laryngol,2010,119(1):64-70. [21] Lourenco BH,Silva LL,Fawzi WW,et al.Vitamin D sufficiency in young Brazilian children:Associated factors and relationship with vitamin A corrected for inflammatory status[J].Public Health Nutrition,2020,23(7):1226-1235. [22] Li XY,Xiao JH,Feng X,et al.Retinoid X receptor-specific ligands synergistically upregulate 1,25-dihydroxyvitamin D3-dependent transcription in epidermal keratinocytes in vitro and in vivo[J].J Invest Dermatol,1997,108(4):506-512. [23] Cantorna MT,Snyder L,Arora J.Vitamin A and vitamin D regulate the microbial complexity,barrier function,and the mucosal immune responses to ensure intestinal homeostasis[J].Crit Rev Biochem Mol Biol,2019,54(2):184-192. [24] Geral DF,Combs JR,Mcclung JP.The vitamins:Fundamental aspects in nutrition and health[M].Sixth Edition,Academic,2022. [25] 古桂雄,戴耀华.普通高等教育“十二五”规划教材:儿童保健学[M].北京:清华大学出版社,2011. [26] Nguyen MTT,Kim J,Lee H,et al.A comparison of vitamin and lutein concentrations in breast milk from four Asian countries[J].Nutrients,2020,12(6):1794. [27] Palacios C,Gonzalez L.Is vitamin D deficiency a major global public health problem?[J]. J Steroid Biochem Mol Biol,2014,144:138-145. [28] Schoor N,Lips P.Global overview of vitamin D status[J].Endocrinol Metab Clin N Am,2017,46:845-870. [29] 李廷玉,谭梅.孤独症谱系障碍儿童微营养素缺乏的监测和干预原则[J].中国儿童保健杂志,2021,29(1):1-4. [30] 汪笛,徐芳.儿童青少年维生素D受体基因多态性与代谢综合征组分的关系[J].中华实用儿科临床杂志,2019,34(12):954-957. [31] Karlsson O,Kim R,Hasman A,et al.Consumption of vitamin-A-rich foods and vitamin A supplementation for children under two years old in 51 low-and middle-income countries[J].Nutrients,2021,14(1):188. [32] Carazo A,Macakova K,Matousova K,et al.Vitamin A update:Forms,sources,kinetics,detection,function,deficiency,therapeutic use and toxicity[J].Nutrients,2021,13(5):1703. [33] DiKun KM, Gudas LJ.Vitamin A and retinoid signaling in the kidneys[J].Pharmacol Ther,2023,248:108481. [34] Rojo-Trejo MH, Robles-Osorio ML, Sabath E.Liposoluble vitamins A and E in kidney disease[J].World J Nephrol,2022,11(3):96-104. [35] Lokman NA,Ho R,Gunasegaran K,et al.Anti-tumour effects of all-trans retinoid acid on serous ovarian cancer[J].J Exp Clin Cancer Res,2019,38(1):10. [36] Takahashi N,Saito D,Hasegawa S,et al.Vitamin A in health care:Suppression of growth and induction of differentiation in cancer cells by vitamin A and its derivatives and their mechanisms of action[J].Pharmacol Ther,2022,230:107942. [37] Dewett D,Lam-Kamath K,Poupault C,et al.Mechanisms of vitamin A metabolism and deficiency in the mammalian and fly visual system[J].Dev Biol,2021,476:68-78. [38] Thirunavukarasu AJ,Ross AC,Gilbert RM.Vitamin A,systemic T-cells,and the eye:Focus on degenerative retinal disease[J].Frontiers in Nutrition,2022,9:914457. [39] 张尚武.学龄前视力发育异常患儿血清VitA水平及危险因素分析[J].检验医学与临床,2019,16(21):3182-3184. [40] Stephensen CB.Vitamin A,infection,and immune function[J].Annu Rev Nutr,2001,21:167-192. [41] Brown CC,Noelle RJ.Seeing through the dark:New insights into the immune regulatory functions of vitamin A[J].Eur J Immunol,2015,45(5):1287-1295. [42] Stephensen CB,Lietz G.Vitamin A in resistance to and recovery from infection:Relevance to SARS-CoV2[J].Br J Nutr,2021,126(11):1663-1672. [43] Yee MMF,Chin KY,Ima-Nirwana S,et al.Vitamin A and bone health:A review on current evidence[J].Molecules,2021,26(6):1757. [44] Ma G,Chen Y,Liu X,et al.Vitamin A supplementation during pregnancy in shaping child growth outcomes:A meta-analysis[J].Crit Rev Food Sci Nutr,2023,63(33):12240-12255. [45] Roche FC,Harris-Tryon TA.Illuminating the role of vitamin A in skin innate immunity and the skin microbiome:A narrative review[J].Nutrients,2021,13(2):302. [46] Szymanski L,Skopek R,Palusinska M,et al.Retinoic acid and its derivatives in skin[J].Cells,2020,9(12):2660. [47] Canete A,Cano E,Munoz-Chapuli R,et al.Role of vitamin A/retinoic acid in regulation of embryonic and adult hematopoiesis[J].Nutrients,2017,9(2):159. [48] da Cunha MSB, Campos Hankins NA, Arruda SF.Effect of vitamin A supplementation on iron status in humans:A systematic review and meta-analysis[J].Crit Rev Food Sci Nutr,2019,59(11):1767-1781. [49] Cheng B,Zhu J,Yang T,et al.Vitamin A deficiency increases the risk of gastrointestinal comorbidity and exacerbates core symptoms in children with autism spectrum disorder[J].Pediatr Res,2021,89(1):211-216. [50] 黎海芪.实用儿童保健学[M].北京:人民卫生出版社,2016. [51] Uday S,Fratzl-Zelman N,Roschger P,et al.Cardiac, bone and growth plate manifestations in hypocalcemic infants: Revealing the hidden body of the vitamin D deficiency iceberg[J].BMC pediatrics,2018,18(1):183. [52] Bouillon R,Marcocci C,Carmeliet G,et al.Skeletal and extraskeletal actions of vitamin D: Current evidence and outstanding questions[J].Endocr Rev,2019,40(4):1109-1151. [53] Pilz S,Zittermann A,Trummer C,et al.Vitamin D testing and treatment:A narrative review of current evidence[J].Endocr Connect,2019,8(2):R27-R43. [54] Ismailova A,White JH.Vitamin D,infections and immunity[J].Rev Endocr Metab Disord,2022,23(2):265-277. [55] Stoica AB,Marginean C.The impact of vitamin D deficiency on infants' health[J].Nutrients,2023,15(20):4379. [56] Albinana C,Boelt SG,Cohen AS,et al.Developmental exposure to vitamin D deficiency and subsequent risk of schizophrenia[J].Schizophr Res,2022,247:26-32. [57] Yasumitsu-Lovell K,Thompson L,Fernell E,et al.Vitamin D deficiency associated with neurodevelopmental problems in 2-year-old Japanese boys[J].Acta Paediatr,2024,113(1):119-126. [58] Bener A,Ehlayel MS,Bener HZ,et al.The impact of vitamin D deficiency on asthma, allergic rhinitis and wheezing in children: An emerging public health problem[J].J Family Community Med,2014,21(3):154-161. [59] Bae KN,Nam HK,Rhie YJ,et al.Low levels of 25-hydroxyvitamin D in children and adolescents with type 1 diabetes mellitus: A single center experience[J].Ann Pediatr Endocrinol Metab,2018,23(1):21-27. [60] Zhou A,Selvanayagam JB,Hypponen E.Non-linear mendelian randomization analyses support a role for vitamin D deficiency in cardiovascular disease risk[J].Eur Heart J, 2022,43(18):1731-1739. [61] Boskabadi H,Mamoori G,Khatami SF,et al.Serum level of vitamin D in preterm infants and its association with premature-related respiratory complications:A case-control study[J].Electron Physician,2018,10(1):6208-6214. [62] Nichols EK, Khatib IM, Aburto NJ, et al.Vitamin D status and associated factors of deficiency among Jordanian children of preschool age[J].European Journal of Clinical Nutrition,2015,69(1):90-95. [63] Stevens GA, Bennett JE, Hennocq Q, et al.Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: A pooled analysis of population-based surveys[J].The Lancet Global Health,2015,3(9):e528-e536. [64] Murguia-Peniche T.Vitamin D,vitamin A,maternal-perinatal considerations: Old concepts, new insights, new questions[J].J Pediatr,2013,162(Suppl 3):26-30. [65] Yakoob MY, Lo CW.Nutrition (Micronutrients) in child growth and development: A systematic review on current evidence, recommendations and opportunities for further research[J].J Dev Behav Pediatr,2017,38(8):665-679. [66] Hardelid P,Dattani N,Cortina-Borja M,et al.Contribution of respiratory tract infections to child deaths:A data linkage study[J].BMC Public Health, 2014,14:1191. [67] Zhang X,Ding F,Li H,et al.Low serum levels of vitamins A, D, and E are associated with recurrent respiratory tract infections in children living in Northern China: A case control study[J].PloS One,2016,11(12):e0167689. [68] Raniszewska A,Gorska E,Kotula I,et al.Recurrent respiratory tract infections in children-analysis of immunological examinations[J].Cent Eur J Immunol,2015,40(2):167-173. [69] Hall JA,Grainger JR,Spencer SP,et al.The role of retinoic acid in tolerance and immunity[J].Immunity,2011,35(1):13-22. [70] Kim KC,McCracken K,Lee BC,et al.Airway goblet cell mucin:Its structure and regulation of secretion[J].Eur Respir J,1997,10(11):2644-2649. [71] Underwood MA,Bevins CL.Defensin-barbed innate immunity:Clinical associations in the pediatric population[J].Pediatrics,2010,125(6):1237-1247. [72] 刘文梅,陈沛.不同年龄反复呼吸道感染患儿血清维生素A、D、E水平变化及其发生预测模型构建[J].中国优生与遗传杂志, 2023,31(6):1202-1207. [73] 杨茜岚,相东晓,谢丹,等.维生素A、D、E与儿童反复呼吸道感染关系的研究[J].医学信息, 2023,36(21):66-69. [74] Maenner MJ, Rice CE, Arneson CL, et al.Potential impact of DSM-5 criteria on autism spectrum disorder prevalence estimates[J].JAMA Psychiatry,2014,71(3):292-300. [75] Liu L,Zhang D,Rodzinka-Pasko JK,et al.Environmental risk factors for autism spectrum disorders[J].Nervenarzt,2016,87(Suppl 2):55-61. [76] Liu X,Liu J,Xiong X,et al.Correlation between nutrition and symptoms: Nutritional survey of children with autism spectrum disorder in Chongqing, China[J].Nutrients,2016,8(5):294. [77] Feng J,Shan L,Du L, et al.Clinical improvement following vitamin D3 supplementation in autism spectrum disorder[J].Nutr Neurosci,2017,20(5):284-290. [78] Guo M,Zhu J,Yang T,et al.Vitamin A and vitamin D deficiencies exacerbate symptoms in children with autism spectrum disorders[J].Nutr Neurosci,2019,22(9):637-647. [79] Guo M,Li L,Zhang Q,et al.Vitamin and mineral status of children with autism spectrum disorder in Hainan Province of China: Associations with symptoms[J].Nutr Neurosci, 2020,23(10):803-810. [80] 侯成,杨召川,刘秀梅,等.血清维生素A、维生素D与抽动障碍症状严重程度、临床类型的相关性研究[J].中华行为医学与脑科学杂志,2020,29(4):308-314. [81] 邓慧玲,张玉凤,宋鹤, 等.维生素A、维生素D水平与柯萨奇病毒A6型手足口病重症化的关联性研究[J].中华实用儿科临床杂志,2020,35(18):1394-1397. [82] 李楠, 荆科.肺炎婴幼儿维生素A、维生素D水平及与肺炎后反复呼吸道感染关系的研究[J].国际儿科学杂志,2020,47(6):441-444. [83] 吕楠,马彩云,李靖婕,等.维生素AD在运动发育迟缓患儿康复治疗中的作用[J].中国儿童保健杂志,2020,47(6):676-679. [84] 余玉盛,卞秋翔,徐勇,等.生长迟缓儿童骨龄、维生素A、维生素D及IGF-1检测分析[J].国际儿科学杂志,2020,47(4):283-287. [85] Zheng Y, Li XG, Wang QZ, et al.Enhancement of vitamin A combined vitamin D supplementation on immune response to Bacille Calmette-Guerin vaccine revaccinated in Chinese infants[J].Asian Pac J Trop Med,2014,7(2):130-135. [86] Patel N, Penkert RR, Jones BG, et al.Baseline serum vitamin A and D levels determine benefit of oral vitamin A&D supplements to humoral immune responses following pediatric influenza vaccination[J].Viruses,2019,11(10):907. [87] Xiang J, Wang H, Li T.Comorbidity of vitamin A and vitamin D deficiency exacerbates the severity of atopic dermatitis in children[J].Dermatology,2019,235(3):196-204. [88] 全国提高儿童生命质量学术会议.亚临床状态维生素A缺乏的防治方案[J].中华儿科杂志,1995,33(4):201. [89] 李廷玉.维生素A缺乏的诊断、治疗及预防[J].中华实用儿科临床杂志,2013,28(19):1519-1520. [90] 中华儿科杂志编辑委员会.早产、低出生体重儿出院后喂养建议[J].中华儿科杂志, 2016,54(1):6-12. [91] 全国佝偻病防治科研协作组.维生素D缺乏及维生素D缺乏性佝偻病防治建议[J].中国儿童保健杂志, 2015,23(7):781-782. [92] 王卫平.儿科学[M].9版.北京: 人民卫生出版社, 2018. [93] 王天有,申昆玲,沈颖.诸福棠实用儿科学[M].9版.北京: 人民卫生出版社, 2022. [94] 熊建平,毕延芹.维生素A中毒1例[J].第三军医大学学报,2001,23(3):330. [95] 中华医学会儿科学分会儿童保健学组.中国儿童维生素D营养相关临床问题实践指南[J].中华儿科杂志,2022,60(5):387-394. [96] Levita J, Wilar G, Wahyuni I, et al.Clinical toxicology of vitamin D in pediatrics: A review and case reports[J].Toxics,2023,11(7):642. [97] Bereket A, Erdogan T.Oral bisphosphonate therapy for vitamin D intoxication of the infant[J].Pediatrics, 2003,111(4 Pt 1):899-901. |
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