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中国临床药理学与治疗学 ›› 2020, Vol. 25 ›› Issue (4): 475-480.doi: 10.12092/j.issn.1009-2501.2020.04.019

• 综述与讲座 • 上一篇    

晚期三阴性乳腺癌的药物治疗进展

赵全铭1,杨 洋2   

  1. 1山西医科大学第二临床学院,太原 030001,山西;2重庆医科大学药学院药理学教研室,重庆 400016
  • 收稿日期:2020-02-21 修回日期:2020-03-15 出版日期:2020-04-26 发布日期:2020-05-12
  • 通讯作者: 杨洋,男,博士,研究方向:抗肿瘤药物研究。 Tel:023-68485161 E-mail:563143323@qq.com
  • 作者简介:赵全铭,男,本科,研究方向:抗肿瘤药物研究。 Tel:0351-4135332 E-mail:zhaoquanming@126.com
  • 基金资助:
    重庆市技术创新与应用发展专项面上项目(cstc2019jscx-msxmX0096)

Progress in drug therapy for advanced triple-negative breast cancer

ZHAO Quanming1, YANG Yang2   

  1. 1Second Clinical Medical College of Shanxi Medical University, Taiyuan 030001, Shanxi, China;  2College of Pharmacy, Chongqing Medical University, Chongqing 400016, China
  • Received:2020-02-21 Revised:2020-03-15 Online:2020-04-26 Published:2020-05-12

摘要: 三阴性乳腺癌为雌、孕激素受体及人表皮生长因子受体-2均为阴性的乳腺癌,由于缺乏特异性的治疗靶点,晚期治疗尚缺少有效的治疗方案。本文综述近年来晚期三阴性乳腺癌的药物治疗研究进展,主要包括化学治疗、靶向治疗、内分泌治疗、免疫治疗四个方面,旨在为临床治疗提供借鉴和参考。

关键词: 三阴性乳腺癌, 化学治疗, 靶向治疗, 内分泌治疗, 免疫治疗

Abstract: Triple-negative breast cancer is estrogen receptor, progesterone receptor and human epidermal growth factor receptor-2 negative breast cancer. The lack of specific treatment targets, there are few effective therapy for advanced triple- negative breast cancer. This article will review the current progress in drug therapy for advanced triple-negative breast cancer, including chemotherapy, targeted therapy, endocrine therapy and immunotherapy, in order to provide reference for clinical treatment.

Key words: triple-negative breast cancer, chemotherapy, targeted therapy, endocrine therapy, immunotherapy

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