盆腔脏器脱垂的相关机制和治疗的研究进展

doi:10.12092/j.issn.1009-2501.2020.05.018

摘要/Abstract

摘要： 盆腔器官脱垂(pelvic organ prolapse, POP)是多种病因导致的盆底支持系统薄弱,女性生殖系统和相邻的脏器发生位置异常,形成子宫脱垂、阴道前后壁膨出等临床疾病。本文对疾病的流行病学及病因、目前治疗手段进行了整体概述,并着重对发病基础机制和间充质干细胞(mesenchymal stem cells, MSCs)在疾病中的应用前景进行了详细的阐述。

关键词: 盆腔脏器脱垂, 间充质干细胞, 机制, 治疗

Abstract: Pelvic organ prolapse (POP) is caused by a variety of causes, such as weak pelvic floor support system, abnormal location of female reproductive system and adjacent organs, uterine prolapse, anterior and posterior vaginal wall prolapse and other clinical diseases. In this paper, the epidemiology, etiology and current treatment of the disease were summarized, and the basic pathogenesis and the application prospect of mesenchymal stem cells (MSCs) in the disease were described in detail.

Key words: pelvic organ prolapse, mesenchymal stem cells, pathogenesis, treatment

中图分类号:

R711.2

周懿雯, 平毅. 盆腔脏器脱垂的相关机制和治疗的研究进展[J]. 中国临床药理学与治疗学, 2020, 25(5): 595-600.

ZHOU Yiwen, PING Yi. Research progress on the mechanism and treatment of pelvic organ prolapse[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2020, 25(5): 595-600.

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