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中国临床药理学与治疗学 ›› 2023, Vol. 28 ›› Issue (12): 1436-1440.doi: 10.12092/j.issn.1009-2501.2023.12.015

• 综述与讲座 • 上一篇    下一篇

丘脑室旁核在全身麻醉和睡眠觉醒神经通路中的作用

顾芸菲1,陈苏衡1,于恺华1,鲍振星1,李玉兰2   

  1. 1兰州大学第一临床医学院,兰州  730000,甘肃; 2兰州大学第一医院麻醉科,兰州  730000,甘肃;
  • 收稿日期:2023-07-10 修回日期:2023-08-25 出版日期:2023-12-26 发布日期:2023-12-21
  • 通讯作者: 李玉兰,女,主任医师,博士生导师,研究方向:麻醉学。 E-mail: jasm@sina.com
  • 作者简介:顾芸菲,女,硕士研究生在读,研究方向:麻醉学。 E-mail: 1183729859@qq.com
  • 基金资助:
    甘肃省卫生健康行业科研项目(GSWSKY2021-079)

Paraventricular thalamic nucleus nerve pathways involved in general anesthesia wakefulness and sleep wakefulness

GU Yunfei1, CHEN Suheng1, YU Kaihua1, BAO Zhenxing1, LI Yulan2   

  1. 1The First Clinical Medical College of Lanzhou University, Lanzhou 730000, Gansu, China; 2Department of Anesthesiology, First Hospital of Lanzhou University, Lanzhou 730000, Gansu, China
  • Received:2023-07-10 Revised:2023-08-25 Online:2023-12-26 Published:2023-12-21

摘要: 丘脑室旁核(paraventricular thalamic nucleus,PVT)是觉醒的关键核团。PVT在正常睡眠的觉醒调节中占据着重要作用,但在麻醉中其作用可能随着所处麻醉阶段的不同而不同。本文将围绕PVT觉醒功能神经通路来综述其在睡眠和麻醉中的作用。

关键词: 丘脑室旁核, 全身麻醉, 睡眠, 觉醒, 意识

Abstract:

The paraventricular thalamic nucleus (PVT) is a key nucleus involved in wakefulness. PVT plays an important role in normal sleep-wake regulation, but its role may vary during anesthesia depending on the stage of anesthesia. This article will review the role of PVT in sleep and anesthesia based on its wakefulness function neural pathways.

Key words: paraventricular thalamic nucleus, general anesthesia, sleep, wakefulness, consciousness

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