关键词: 血塞通滴丸, 心绞痛, 中药疗法, 药物不良反应, 临床试验

Abstract: AIM: To evaluate the efficacy and safety of xuesetong pills in the treatment of patients with angina pectoris.METHODS: Regard xuesetong tablet as contrast, xuesetong pill was observed in a random, doubleblind, double-modeling, positive drug parallel contrast and multi-center clinical trial.RESULTS: The total effective rate of xuesetong pill was 82. 1 %on angina pectoris and 67. 2 % on the amelioration of ECG, and there was no significant difference on the symptoms and ECG between the two groups (P >0. 05). Xuesetong pill can significantly relieve the symptoms of angina pectoris, and the total effective rate of xuesetong pill was 86. 6 %on the symptoms of the traditional Chinese medicine. Comparing with the xuesetong tablet, xuesetong pill can markedly relieve the symptoms of the traditional Chinese medicine after the treatment of xuesetong pills for 1 week, and there was a significant difference on the symptoms of the traditional Chinese medicine and the amount of the symptoms of the traditional Chinese medicine between the two groups (P<0. 01). But there was no marked difference after the treatment of xuesetong pills for 4 weeks (P >0. 05). The blow result time of xuesetong pill is superior to that of the xuesetong tablet (P<0. 01). No serious side effects on general health exam, blood-routine, urine-routine, stool-routine, liver function and kidney function were observed in the two groups.CONCLUSION: Xuesetong pill has a characteristic of safe, effective, fast result blowing in the treatment of angina pectoris.

Key words: xuesetong pill, angina pectoris, TCD therapy, adverse drug reaction, clinical trial