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中国临床药理学与治疗学 ›› 2017, Vol. 22 ›› Issue (11): 1283-1291.

• 医院药学之窗 • 上一篇    下一篇

骨科清洁手术围手术期预防应用抗菌药物干预效果评价

李 静,高赟赟   

  1. 解放军第八十九医院药剂科,潍坊 261021,山东
  • 收稿日期:2017-05-10 修回日期:2017-06-16 出版日期:2017-11-26 发布日期:2017-12-11
  • 通讯作者: 高赟赟,女,硕士研究生,临床药师,研究方向:临床药学。 Tel:0536-8439169 E-mail:gaoyunyun12@126.com
  • 作者简介:李静,女,硕士研究生,主管药师,研究方向:临床药学。 Tel:0536-8439169 E-mail:applemumu@163.com

Interventive effect of preventing application of antibacterials during perioperative period in orthopedics

LI Jing, GAO Yunyun   

  1. Eighty-Ninth Hospital of Chinese People's Liberation Army, Department of Pharmacy, Weifang 261021, Shandong, China
  • Received:2017-05-10 Revised:2017-06-16 Online:2017-11-26 Published:2017-12-11

摘要:

目的:评价某三级甲等医院骨科在实施规范化管理前后清洁手术围手术期预防应用抗菌药物的合理用药情况。方法:对2016年1-3月和2016年10-12月期间骨科清洁手术出院病例进行回顾性研究,对清洁手术围手术期抗菌药物的预防使用率、抗菌药物使用频次、预防用药合理率、适应症选择合理率、用药时机合理率、品种选择合理率、用药疗程合理率进行对照研究。结果:经过规范化管理,骨科各组清洁手术抗菌药物预防使用率有所下降,抗菌药物选择趋于合理,抗菌药物使用合理率显著提高,适应症选择合理率均达到了83%以上,用药时机正确率也有较大提高,品种选择和用药疗程的合理率各组均显著提高(P<0.01)。结论:干预后骨科各组清洁手术抗菌药物使用的合理性显著提高,干预措施取得明显效果。

关键词: 清洁手术, 围手术期, 抗菌药物, 合理用药

Abstract:

AIM: To evaluate the rational use of antibacterials during the perioperative period of clean surgery before and after the implementation of standardized management in the department of orthopedics of a 3A hospital.  METHODS: A retrospective study of orthopedic surgery was conducted from January to March in 2016 and from October to December in 2016. A comparative study was made on the prophylactic use of antibacterials during the perioperative period of clean surgery, antimicrobial use frequency, the rate of rational drug use, rational choice of indications, the first dose time of medication, the species selection of antibacterials and the course of medication. RESULTS: Through the standardized management, the rate of prophylactic use of antibacterials during the perioperative period of clean surgery was decreased, the selection of antibacterials tended to be reasonable, and the rate of rational use of antibacterials was significantly improved. The rate of rational choice of indications was reached more than 83%. The correct rate of first dose time was greatly improved as well as the species selection and the course of medication (P<0.01). CONCLUSION: The rationality of the use of antimicrobial agents in orthopedics is significantly improved after the intervention and the intervention achieves good results.

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