关键词: 呼吸道感染, 外感风热证, 呼吸系统药, 安全, 随机对照试验, 药物评价, 热毒宁注射液

Abstract: AIM: To evaluate the efficacy and safety of Reduning injection in treating acute upper respiratory tract infections.METHODS: Seventy-one patients were randomly assigned to two groups.Fifty-three patients in trial group were administrated with Redunimg injection 20 ml, iv gtt, qd, while the other in control group were administrated with Qingkailing injection 30ml, iv gtt, qd. The period of treatment was 3 d for each group.RESULTS: On d 3 after treatment, the total clinical effective rate were 98 % in the trial group and 94 % in the control group with significant difference between two groups (P <0.01), while the total effective rate of Chinese traditional medical symptoms were 98 % in the trial group and 94 % in the control group with significant difference between two groups (P <0.05).In trial and control groups no adverse reactions was found.CONCLUSION: Reduning injection is an effective and safe agent in treatment of patients with acute upper respiratory tract infections.

Key words: respiratory tract infections, respiratory system agents, safety, randomized controlled trials, drug evaluation, Reduning injection