Welcome to Chinese Journal of Clinical Pharmacology and Therapeutics,Today is Chinese

Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2018, Vol. 23 ›› Issue (12): 1380-1385.doi: 10.12092/j.issn.1009-2501.2018.12.011

Previous Articles     Next Articles

Clinical study of lipid type artificial tear in cataract patients with postoperative dry eye by phacoemulsification

CHEN Zhanqiao, ZHONG Liumei, LI Xia, YING Jinhe   

  1. Department of Ophthalmology, Lishui Central Hospital, Lishui 323000, Zhejiang, China
  • Received:2018-07-18 Revised:2018-10-29 Online:2018-12-26 Published:2018-12-27

Abstract:

AIM: To investigate the clinical effect of lipid artificial tears on patients with dry eye after phacoemulsification.  METHODS: A total of 90 cases of dry eyes after cataract surgery were selected after phacoemulsification in our hospital from March 2015 to May 2017 and they were divided into observation group (45 cases) and control group (45 cases) according to the random number table method, the control group used sodium hyaluronate eye drops, the observation group used lipid type artificial tears (gel carbomer), the two groups were tested for ocular surface disease index (OSDI), break-up time (BUT), corneal fluorescein staining (CFS) and schirmer I test (SIT) at preoperative, one week after operation, one month after operation and three months after operation. RESULTS:The total effective rate of observation group (88.1%) was significantly higher than that (65.0%) of control group (P<0.05); one week after operation, there was no statistically significant difference in OSDI scores between the two groups (P>0.05); one month and three months after operation, OSDI scores in both groups were significantly lower than one week after operation (P<0.05), and the OSDI score of observation group was significantly lower than that of control group (P<0.05); one week, one month and three months after operation, the BUT of observation group were significantly higher than those of control group (P<0.05); one week, one month and three months after operation, the CFS scores of observation group were significantly lower than those of control group (P<0.05); one week after operation, there was no statistically significant difference in SIT experiment results between the two groups (P>0.05); one month and three months after operation, the results of the SIT experiment were significantly better than that of control group (P<0.05). CONCLUSION: Lipid-type artificial tear is effective in treating patients with dry eye after phacoemulsification, and it can obviously alleviate the patient's dry eye symptoms and helps the recovery of tear film, which is worthy of clinical promotion.

Key words: lipid type artificial tear, phacoemulsification, cataract, postoperative dry eye

CLC Number: