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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2021, Vol. 26 ›› Issue (3): 341-349.doi: 10.12092/j.issn.1009-2501.2021.03.015

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Review of bleeding events in clinical studies of clopidogrel

YUAN Zhen, CHEN Bilian   

  1. Department of Geriatrics, Xiangya Hospital, Central South University, Changsha 410078, Hunan, China
  • Received:2020-12-21 Revised:2021-02-06 Online:2021-03-26 Published:2021-04-06

Abstract: P2Y12 receptor antagonist is currently one of the commonly used drugs for the treatment of acute coronary syndromes. Clopidogrel is a representative drug among P2Y12 receptor antagonists. Bleeding events as the most common side effect of this drug have also been concerned. The incidence and risk of bleeding events in large-scale clinical studies of clopidogrel are analyzed and discussed to provide refer-ences for reasonable clinical prescription of clopidogrel. 

Key words: clopidogrel, bleeding events, bleeding definition

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