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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2021, Vol. 26 ›› Issue (4): 462-468.doi: 10.12092/j.issn.1009-2501.2021.04.015

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Research progress on extraction methods and pharmacological activities of polysaccharide from traditional Chinese herb compound

JING Yongshuai 1, ZHANG Yuwei 1, WU Lanfang 2, ZHANG Ruijuan 1, MA Yunfeng 1, ZHANG Danshen 1   

  1. 1 College of Chemistry and Pharmaceutical Engineering, Hebei University of Science and Technology, Shijiazhuang 050018, Hebei, China; 2 College of Pharmacology, Hebei University of Chinese Medicine, Shijiazhuang 050200, Hebei, China
  • Received:2021-01-18 Revised:2021-03-05 Online:2021-04-26 Published:2021-05-11

Abstract: Traditional Chinese herb compound is a prescription formulated according to the theory of Chinese medicine, and it is a commonly used method of Chinese medicine. As one of the main active ingredients, the extraction methods of polysaccharides from traditional Chinese herb compound include solvent extraction, ultrasonic assisted extraction, microwave assisted extraction and microbial fermentation extraction. The traditional Chinese herb compound polysaccharide has antitumor, immunoregulatory, intestinal mucosa repair, hypoglycemic, antiviral, antioxidant and other pharmacological activities. In this paper, the extraction methods of polysaccharides from traditional Chinese herb compound and its pharmacological activities were summarized, so as to provide scientific evidence for a better development and utilization of traditional Chinese herb compound polysaccharide. 

Key words: traditional Chinese herb compound, polysaccharide, extraction method, pharmacological activity

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