Abstract: Aim The influence of the compound Zhenqi oral liquid both on the antineoplastic activity of chemotherapy drugs MMC and CTX and on certain senility indexes was to be observed. Method Antineoplastic activity of the compoud used alone and in combination with MMC and CTX and its immunlogical function were observed in both senile(18 months)and young (1 month) mouse transplanted tumor models. The MDA content was detected by MDA-TSA colorimetry,SOD activity by photoreduced NBT method, and MAO-B activity by spec-trophotometry. Result It was revealed that the compound Zhenqi liquid obviously increased the antineoplastic activity of MMC and CTX, decreased the MDA concentration in tissues of mouse internal organs, inhibited the MAO0-B activity, enhanced SOD activity and prevented the immusuppress induced by MMC and CTX. Conclusion The compoud Zhenqi oral liquid has the properties of synergia, detoxification and antisenility which result from its enhance of immunological function and regulation of metabolism and related enzymatic activity.

Key words: Compound Zhenqi oral liquid, Immunological function, Antineoplastic activity, Antisenility