Abstract: Aim The effect of capsule bushenyanshou (BSYS) on the antioxidative function, and the tolerance of cold and fatigue in rats was investigated. Methods The activity of erythro-cytic superoxide dismutase (SOD), the contents of brain and liver malondialdehyde (MDA) in rats and the changes of body weight, body temperature and the swimming time at (TC in mice were measured. Results Capsule BSYS(400, 800 mg/kg, ig, qd × 21d) increased erythrocytic SOD activity and markedly reduced brain and liver homogenate MDA contents in ole rat and enhanced ihe body weight and body temperature, and prolonged the swim-ming time at 0℃ in hydrocortisone-treated(15 mg/kg, sc, qd × 5 d) mice. Conclusion Capsule BSYS has a certain antisenescent action.

Key words: capsule bushenyanshou, antisenescent action, erythrocytic superoxide dis-murase, malondialdehyde, hydrocortisone-treated mice