Abstract: Aim To evaluate the influence of asthma and the effect of anti-inflammation therapy on the quality of life (QOL)in allergic asthma patients.Methods The QOL of 45 patients with asthma were investigated by collecting questionnaire before and after three months anti-inflammation treatment, at the same time the serum eosinophil cationic protein(ECP) level was detected in 20 patients.The QOL questionnaire included 4 domains, they were respiratory symptoms, physical activity limitation, emotional function and environmental stimuli.Results The factors which influenced the QOL in asthma patients ranging from high to low were environmental stimuli, respiratory symptom and emotion function and physical activity limitation.After anti-inflammation treatment, the QOL was significantly improved and the serum ECP was decreased (P<0.001 and P<0.01).Al though the male patient, those the aging more than 50 and those with advanced education had relatively higher score, there was no significant difference amongsex, age and education before and after anti-inflammation treatment.Conclusion Asthma not only severe impacts patient shealth, but also affects patient diary, social activity and emotional function.Anti-inflammation treatment would significant improve the QOL for asthma patients.

Key words: asthma, quality of life, Anti-inflammation therapy