Abstract: AIM: To observe the influence of cal-citriol (1, 25-(OH) 2D3) on calcium phosphorus metabolism andimmunologic function of peritoneal dialy-sis (PD) patients.METHODS: The level of serum T cell subpopulation, IL-8, immunoreactive parathyroid hormone(iPTH), calcium, and phosphorus were observed before and after patients taking calcitriol.RESULTS: Before taking medicine, CD4/CD8 of group PD was lower than that of normal comparing group (P<0.05);4 weeks after taking calcitriol, CD4/CD8 rised from 0.56±0.10 to 0.79±0.12, andiPTH clearly reduces, while blood calcium, and blood phosphorus obviously goes down as well.CONCLUSION: Calcitriol is able to improve the calcium phosphorus metabolism of PD patients, and their immunologic function.

Key words: peritoneal dialysis, Tlymphocyte sub-groups, interleukin-2, calcitriol